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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC13 All Species: 37.27
Human Site: S223 Identified Species: 58.57
UniProt: P55735 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55735 NP_001129704.1 322 35541 S223 R D V A W A P S I G L P T S T
Chimpanzee Pan troglodytes XP_516277 314 34654 S212 E Q K L E A H S D W V R D V A
Rhesus Macaque Macaca mulatta XP_001089862 325 35829 S226 R D V A W A P S I G L P T S T
Dog Lupus familis XP_850437 322 35501 S223 R D V A W A P S I G L P T S T
Cat Felis silvestris
Mouse Mus musculus Q9D1M0 322 35547 S223 R D V A W A P S I G L P T S T
Rat Rattus norvegicus Q5XFW8 322 35529 S223 R D V A W A P S I G L P T S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509095 346 38353 S248 R D V A W A P S I G L P T S T
Chicken Gallus gallus XP_414450 435 46576 S337 R D V A W A P S I G L P T S T
Frog Xenopus laevis Q4FZW5 360 39707 N230 H D I A F A P N L G R S F H I
Zebra Danio Brachydanio rerio Q6TGU2 364 39798 N230 H D I A F A P N L G R S F H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651977 356 39509 S223 R D V A W A P S I G L P R S Q
Honey Bee Apis mellifera XP_393516 311 34288 W209 K L E A H S D W V R D V A W A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788763 325 35667 S221 R D V A W A P S I G L P H S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04491 297 33025 T199 Q T Y V L E S T L E G H S D W
Red Bread Mold Neurospora crassa Q7RZF5 304 33367 G201 T F D P A T N G Y K L E R E P
Conservation
Percent
Protein Identity: 100 96.2 98.1 97.8 N.A. 96.8 97.1 N.A. 85.2 69.1 31.6 31 N.A. 51.4 64.9 N.A. 71.6
Protein Similarity: 100 97.1 98.1 98.7 N.A. 99 99 N.A. 91.6 71.9 48.8 49.1 N.A. 66.5 81 N.A. 87.3
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 100 100 33.3 33.3 N.A. 86.6 6.6 N.A. 86.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 100 60 60 N.A. 86.6 26.6 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 49.6 48.1
Protein Similarity: N.A. N.A. N.A. N.A. 64.2 65.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 80 7 80 0 0 0 0 0 0 7 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 74 7 0 0 0 7 0 7 0 7 0 7 7 0 % D
% Glu: 7 0 7 0 7 7 0 0 0 7 0 7 0 7 0 % E
% Phe: 0 7 0 0 14 0 0 0 0 0 0 0 14 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 0 74 7 0 0 0 0 % G
% His: 14 0 0 0 7 0 7 0 0 0 0 7 7 14 0 % H
% Ile: 0 0 14 0 0 0 0 0 60 0 0 0 0 0 7 % I
% Lys: 7 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % K
% Leu: 0 7 0 7 7 0 0 0 20 0 67 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 14 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 0 74 0 0 0 0 60 0 0 7 % P
% Gln: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 60 0 0 0 0 0 0 0 0 7 14 7 14 0 0 % R
% Ser: 0 0 0 0 0 7 7 67 0 0 0 14 7 60 0 % S
% Thr: 7 7 0 0 0 7 0 7 0 0 0 0 47 0 47 % T
% Val: 0 0 60 7 0 0 0 0 7 0 7 7 0 7 14 % V
% Trp: 0 0 0 0 60 0 0 7 0 7 0 0 0 7 7 % W
% Tyr: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _