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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC13
All Species:
27.88
Human Site:
S254
Identified Species:
43.81
UniProt:
P55735
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55735
NP_001129704.1
322
35541
S254
D
A
S
S
N
T
W
S
P
K
L
L
H
K
F
Chimpanzee
Pan troglodytes
XP_516277
314
34654
W243
Q
D
G
R
V
F
I
W
T
C
D
D
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001089862
325
35829
S257
D
A
S
G
N
T
W
S
P
K
L
L
H
K
F
Dog
Lupus familis
XP_850437
322
35501
S254
D
T
S
G
N
T
W
S
P
K
L
L
H
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1M0
322
35547
S254
D
A
S
G
N
M
W
S
P
K
L
L
H
K
F
Rat
Rattus norvegicus
Q5XFW8
322
35529
S254
D
A
S
G
N
M
W
S
P
K
L
L
H
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509095
346
38353
N279
E
A
S
G
S
T
W
N
P
K
L
L
H
K
F
Chicken
Gallus gallus
XP_414450
435
46576
S368
D
A
S
G
S
S
W
S
P
K
L
L
H
K
F
Frog
Xenopus laevis
Q4FZW5
360
39707
G261
R
K
E
L
S
S
S
G
G
V
T
K
F
E
I
Zebra Danio
Brachydanio rerio
Q6TGU2
364
39798
S261
R
R
E
S
A
N
S
S
G
P
T
K
F
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651977
356
39509
S254
A
D
L
S
E
W
T
S
T
V
L
H
T
F
D
Honey Bee
Apis mellifera
XP_393516
311
34288
S240
R
R
V
I
V
W
T
S
N
D
Y
T
S
W
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788763
325
35667
T252
E
G
T
G
S
T
W
T
P
K
I
L
N
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04491
297
33025
T230
A
S
V
S
Q
D
R
T
C
I
I
W
T
Q
D
Red Bread Mold
Neurospora crassa
Q7RZF5
304
33367
A232
V
L
Q
K
S
Y
I
A
S
A
S
Q
D
K
T
Conservation
Percent
Protein Identity:
100
96.2
98.1
97.8
N.A.
96.8
97.1
N.A.
85.2
69.1
31.6
31
N.A.
51.4
64.9
N.A.
71.6
Protein Similarity:
100
97.1
98.1
98.7
N.A.
99
99
N.A.
91.6
71.9
48.8
49.1
N.A.
66.5
81
N.A.
87.3
P-Site Identity:
100
0
93.3
86.6
N.A.
86.6
86.6
N.A.
73.3
80
0
13.3
N.A.
20
6.6
N.A.
46.6
P-Site Similarity:
100
0
93.3
86.6
N.A.
86.6
86.6
N.A.
93.3
93.3
20
20
N.A.
20
6.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.6
48.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.2
65.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
40
0
0
7
0
0
7
0
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% C
% Asp:
40
14
0
0
0
7
0
0
0
7
7
7
7
0
14
% D
% Glu:
14
0
14
0
7
0
0
0
0
0
0
0
0
14
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
14
7
54
% F
% Gly:
0
7
7
47
0
0
0
7
14
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
47
0
0
% H
% Ile:
0
0
0
7
0
0
14
0
0
7
14
0
0
0
7
% I
% Lys:
0
7
0
7
0
0
0
0
0
54
0
14
0
60
0
% K
% Leu:
0
7
7
7
0
0
0
0
0
0
54
54
0
0
0
% L
% Met:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
34
7
0
7
7
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
54
7
0
0
0
0
0
% P
% Gln:
7
0
7
0
7
0
0
0
0
0
0
7
0
7
0
% Q
% Arg:
20
14
0
7
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
47
27
34
14
14
60
7
0
7
0
7
7
7
% S
% Thr:
0
7
7
0
0
34
14
14
14
0
14
7
14
0
14
% T
% Val:
7
0
14
0
14
0
0
0
0
14
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
14
54
7
0
0
0
7
0
7
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _