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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC13
All Species:
20.3
Human Site:
S309
Identified Species:
31.9
UniProt:
P55735
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55735
NP_001129704.1
322
35541
S309
D
V
N
K
G
Q
G
S
V
S
A
S
V
T
E
Chimpanzee
Pan troglodytes
XP_516277
314
34654
V298
E
S
V
D
G
Q
W
V
C
I
S
D
V
N
K
Rhesus Macaque
Macaca mulatta
XP_001089862
325
35829
S312
D
V
N
K
G
Q
G
S
V
S
A
S
V
T
E
Dog
Lupus familis
XP_850437
322
35501
S309
D
V
N
K
G
Q
G
S
V
S
A
S
V
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1M0
322
35547
S309
D
V
N
K
G
Q
G
S
V
S
A
S
I
T
E
Rat
Rattus norvegicus
Q5XFW8
322
35529
S309
D
V
N
K
G
Q
G
S
V
S
A
S
I
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509095
346
38353
A334
D
V
N
K
G
Q
G
A
V
S
A
I
T
D
G
Chicken
Gallus gallus
XP_414450
435
46576
G423
D
V
N
K
G
Q
G
G
V
S
A
V
P
E
G
Frog
Xenopus laevis
Q4FZW5
360
39707
I316
Y
M
D
N
W
K
C
I
G
V
L
K
G
D
G
Zebra Danio
Brachydanio rerio
Q6TGU2
364
39798
T316
Y
M
D
N
W
K
C
T
G
I
L
R
G
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651977
356
39509
S309
E
S
G
T
A
I
Q
S
K
Q
P
S
H
L
P
Honey Bee
Apis mellifera
XP_393516
311
34288
E295
G
Q
W
I
C
I
S
E
T
N
K
G
Q
G
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788763
325
35667
Q307
D
V
N
K
G
E
G
Q
S
Q
T
T
Q
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04491
297
33025
L285
V
T
L
W
K
E
N
L
E
G
K
W
E
P
A
Red Bread Mold
Neurospora crassa
Q7RZF5
304
33367
L287
S
D
N
N
K
V
T
L
W
K
E
N
L
K
G
Conservation
Percent
Protein Identity:
100
96.2
98.1
97.8
N.A.
96.8
97.1
N.A.
85.2
69.1
31.6
31
N.A.
51.4
64.9
N.A.
71.6
Protein Similarity:
100
97.1
98.1
98.7
N.A.
99
99
N.A.
91.6
71.9
48.8
49.1
N.A.
66.5
81
N.A.
87.3
P-Site Identity:
100
20
100
100
N.A.
93.3
93.3
N.A.
66.6
66.6
0
0
N.A.
13.3
0
N.A.
40
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
73.3
66.6
20
26.6
N.A.
20
6.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.6
48.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.2
65.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
7
0
0
47
0
0
0
7
% A
% Cys:
0
0
0
0
7
0
14
0
7
0
0
0
0
0
0
% C
% Asp:
54
7
14
7
0
0
0
0
0
0
0
7
0
20
0
% D
% Glu:
14
0
0
0
0
14
0
7
7
0
7
0
7
7
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
0
60
0
54
7
14
7
0
7
14
7
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
7
0
14
0
7
0
14
0
7
14
0
0
% I
% Lys:
0
0
0
54
14
14
0
0
7
7
14
7
0
7
7
% K
% Leu:
0
0
7
0
0
0
0
14
0
0
14
0
7
7
0
% L
% Met:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
60
20
0
0
7
0
0
7
0
7
0
7
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
0
7
7
14
% P
% Gln:
0
7
0
0
0
54
7
7
0
14
0
0
14
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
7
14
0
0
0
0
7
40
7
47
7
40
0
7
0
% S
% Thr:
0
7
0
7
0
0
7
7
7
0
7
7
7
34
0
% T
% Val:
7
54
7
0
0
7
0
7
47
7
0
7
27
0
0
% V
% Trp:
0
0
7
7
14
0
7
0
7
0
0
7
0
0
0
% W
% Tyr:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _