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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC13 All Species: 19.39
Human Site: T315 Identified Species: 30.48
UniProt: P55735 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55735 NP_001129704.1 322 35541 T315 G S V S A S V T E G Q Q N E Q
Chimpanzee Pan troglodytes XP_516277 314 34654 N304 W V C I S D V N K G Q G S V S
Rhesus Macaque Macaca mulatta XP_001089862 325 35829 T318 G S V S A S V T E G Q Q N E Q
Dog Lupus familis XP_850437 322 35501 T315 G S V S A S V T E G Q Q N E Q
Cat Felis silvestris
Mouse Mus musculus Q9D1M0 322 35547 T315 G S V S A S I T E G Q Q N E Q
Rat Rattus norvegicus Q5XFW8 322 35529 T315 G S V S A S I T E G Q Q N E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509095 346 38353
Chicken Gallus gallus XP_414450 435 46576
Frog Xenopus laevis Q4FZW5 360 39707 D322 C I G V L K G D G N P V G N S
Zebra Danio Brachydanio rerio Q6TGU2 364 39798 D322 C T G I L R G D G S P V N G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651977 356 39509 L315 Q S K Q P S H L P H S H S Q Q
Honey Bee Apis mellifera XP_393516 311 34288 G301 S E T N K G Q G N L N N T D Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788763 325 35667 S313 G Q S Q T T Q S P A I T A T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04491 297 33025
Red Bread Mold Neurospora crassa Q7RZF5 304 33367 K293 T L W K E N L K G E W E N V K
Conservation
Percent
Protein Identity: 100 96.2 98.1 97.8 N.A. 96.8 97.1 N.A. 85.2 69.1 31.6 31 N.A. 51.4 64.9 N.A. 71.6
Protein Similarity: 100 97.1 98.1 98.7 N.A. 99 99 N.A. 91.6 71.9 48.8 49.1 N.A. 66.5 81 N.A. 87.3
P-Site Identity: 100 20 100 100 N.A. 93.3 93.3 N.A. 0 0 0 6.6 N.A. 20 6.6 N.A. 6.6
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. 0 0 0 13.3 N.A. 33.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 49.6 48.1
Protein Similarity: N.A. N.A. N.A. N.A. 64.2 65.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 0 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 34 0 0 0 0 7 0 0 7 0 0 % A
% Cys: 14 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 14 0 0 0 0 0 7 0 % D
% Glu: 0 7 0 0 7 0 0 0 34 7 0 7 0 34 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 40 0 14 0 0 7 14 7 20 40 0 7 7 7 0 % G
% His: 0 0 0 0 0 0 7 0 0 7 0 7 0 0 0 % H
% Ile: 0 7 0 14 0 0 14 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 7 7 7 7 0 7 7 0 0 0 0 0 7 % K
% Leu: 0 7 0 0 14 0 7 7 0 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 7 7 7 7 7 47 7 0 % N
% Pro: 0 0 0 0 7 0 0 0 14 0 14 0 0 0 0 % P
% Gln: 7 7 0 14 0 0 14 0 0 0 40 34 0 7 47 % Q
% Arg: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 40 7 34 7 40 0 7 0 7 7 0 14 0 20 % S
% Thr: 7 7 7 0 7 7 0 34 0 0 0 7 7 7 0 % T
% Val: 0 7 34 7 0 0 27 0 0 0 0 14 0 14 0 % V
% Trp: 7 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _