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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC13
All Species:
28.18
Human Site:
Y178
Identified Species:
44.29
UniProt:
P55735
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55735
NP_001129704.1
322
35541
Y178
P
S
G
Q
K
P
N
Y
I
K
R
F
A
S
G
Chimpanzee
Pan troglodytes
XP_516277
314
34654
Y178
P
S
G
Q
K
P
N
Y
I
K
R
F
A
S
G
Rhesus Macaque
Macaca mulatta
XP_001089862
325
35829
Y181
P
S
G
Q
K
P
N
Y
I
K
R
F
A
S
G
Dog
Lupus familis
XP_850437
322
35501
Y178
P
S
G
Q
K
P
N
Y
I
K
K
F
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1M0
322
35547
Y178
P
S
G
Q
K
P
N
Y
I
K
K
F
A
S
G
Rat
Rattus norvegicus
Q5XFW8
322
35529
Y178
P
S
G
Q
K
P
N
Y
I
K
K
F
A
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509095
346
38353
F203
P
S
G
H
K
P
H
F
I
K
K
F
A
S
G
Chicken
Gallus gallus
XP_414450
435
46576
Y293
P
S
G
Q
K
P
N
Y
I
K
R
F
A
S
G
Frog
Xenopus laevis
Q4FZW5
360
39707
H178
N
P
S
S
S
R
A
H
S
P
M
I
A
V
G
Zebra Danio
Brachydanio rerio
Q6TGU2
364
39798
H178
N
P
S
S
S
R
A
H
P
P
M
I
A
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651977
356
39509
A178
Q
R
V
T
S
R
S
A
A
V
K
R
L
V
S
Honey Bee
Apis mellifera
XP_393516
311
34288
R177
Q
R
N
G
P
I
K
R
L
A
T
G
G
C
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788763
325
35667
V178
T
G
Q
K
P
N
L
V
R
R
F
V
T
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04491
297
33025
H164
T
I
E
E
D
G
E
H
N
G
T
K
E
S
R
Red Bread Mold
Neurospora crassa
Q7RZF5
304
33367
S169
T
P
G
S
I
V
S
S
N
P
G
P
G
S
T
Conservation
Percent
Protein Identity:
100
96.2
98.1
97.8
N.A.
96.8
97.1
N.A.
85.2
69.1
31.6
31
N.A.
51.4
64.9
N.A.
71.6
Protein Similarity:
100
97.1
98.1
98.7
N.A.
99
99
N.A.
91.6
71.9
48.8
49.1
N.A.
66.5
81
N.A.
87.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
73.3
100
13.3
13.3
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
20
20
N.A.
13.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.6
48.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.2
65.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
14
7
7
7
0
0
67
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
0
0
7
7
0
0
7
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
7
54
0
0
0
% F
% Gly:
0
7
60
7
0
7
0
0
0
7
7
7
14
7
74
% G
% His:
0
0
0
7
0
0
7
20
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
7
0
0
54
0
0
14
0
0
0
% I
% Lys:
0
0
0
7
54
0
7
0
0
54
34
7
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
7
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% M
% Asn:
14
0
7
0
0
7
47
0
14
0
0
0
0
0
0
% N
% Pro:
54
20
0
0
14
54
0
0
7
20
0
7
0
0
0
% P
% Gln:
14
0
7
47
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
0
20
0
7
7
7
27
7
0
0
7
% R
% Ser:
0
54
14
20
20
0
14
7
7
0
0
0
0
67
7
% S
% Thr:
20
0
0
7
0
0
0
0
0
0
14
0
7
0
7
% T
% Val:
0
0
7
0
0
7
0
7
0
7
0
7
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _