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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC13 All Species: 45.76
Human Site: Y23 Identified Species: 71.9
UniProt: P55735 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55735 NP_001129704.1 322 35541 Y23 I H D A Q M D Y Y G T R L A T
Chimpanzee Pan troglodytes XP_516277 314 34654 Y23 I H D A Q M D Y Y G T R L A T
Rhesus Macaque Macaca mulatta XP_001089862 325 35829 Y26 I H D A Q M D Y Y G T R L A T
Dog Lupus familis XP_850437 322 35501 Y23 I H D A Q M D Y Y G T R L A T
Cat Felis silvestris
Mouse Mus musculus Q9D1M0 322 35547 Y23 I H D A Q M D Y Y G T R L A T
Rat Rattus norvegicus Q5XFW8 322 35529 Y23 I H D A Q M D Y Y G T R L A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509095 346 38353 Y48 I H D A Q M D Y Y G T R L A T
Chicken Gallus gallus XP_414450 435 46576 Y138 I H D A Q M D Y Y G T R L A T
Frog Xenopus laevis Q4FZW5 360 39707 T29 F H G R R M A T C S S D Q S V
Zebra Danio Brachydanio rerio Q6TGU2 364 39798 R26 S Y D F H G R R M A T C S S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651977 356 39509 F23 V H H A A L D F Y G L L L A T
Honey Bee Apis mellifera XP_393516 311 34288 Y23 I H D A E M D Y Y G L R L A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788763 325 35667 Y23 I H D A Q M D Y Y G I R L A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04491 297 33025 R23 V L D Y Y G K R L A T C S S D
Red Bread Mold Neurospora crassa Q7RZF5 304 33367 Y24 I H D A V L D Y Y G R R L A T
Conservation
Percent
Protein Identity: 100 96.2 98.1 97.8 N.A. 96.8 97.1 N.A. 85.2 69.1 31.6 31 N.A. 51.4 64.9 N.A. 71.6
Protein Similarity: 100 97.1 98.1 98.7 N.A. 99 99 N.A. 91.6 71.9 48.8 49.1 N.A. 66.5 81 N.A. 87.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 13.3 13.3 N.A. 53.3 86.6 N.A. 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 33.3 26.6 N.A. 73.3 93.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 49.6 48.1
Protein Similarity: N.A. N.A. N.A. N.A. 64.2 65.5
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 80
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 80 7 0 7 0 0 14 0 0 0 80 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 14 0 0 0 % C
% Asp: 0 0 87 0 0 0 80 0 0 0 0 7 0 0 14 % D
% Glu: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 7 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 14 0 0 0 80 0 0 0 0 0 % G
% His: 0 87 7 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 74 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 7 0 0 0 14 0 0 7 0 14 7 80 0 0 % L
% Met: 0 0 0 0 0 74 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 60 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 7 7 0 7 14 0 0 7 74 0 0 0 % R
% Ser: 7 0 0 0 0 0 0 0 0 7 7 0 14 20 0 % S
% Thr: 0 0 0 0 0 0 0 7 0 0 67 0 0 0 80 % T
% Val: 14 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 7 0 0 74 80 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _