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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHP2L1 All Species: 63.33
Human Site: Y80 Identified Species: 92.89
UniProt: P55769 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55769 NP_001003796.1 128 14174 Y80 C E D K N V P Y V F V R S K Q
Chimpanzee Pan troglodytes XP_515161 272 30171 Y224 C E D K N V P Y V F V R S K Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CRB2 153 17229 Y105 C E D Q N L P Y V Y I P S K T
Rat Rattus norvegicus XP_001053559 128 14190 Y80 C E D K N V P Y V F V H S K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507848 129 14087 Y81 C E D K N V P Y V F V R S K Q
Chicken Gallus gallus XP_416225 128 14056 Y80 C E D K N V P Y V F V R S K Q
Frog Xenopus laevis Q5XH16 128 14050 Y80 C E D K N V P Y V F V R S K Q
Zebra Danio Brachydanio rerio Q6PBV6 150 16670 Y102 C E D R S L P Y A Y V P S K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U3Z7 127 13865 Y79 C E D K N V P Y V F V R S K Q
Honey Bee Apis mellifera XP_396907 127 13911 Y79 C E D K N V P Y V F V R S K Q
Nematode Worm Caenorhab. elegans Q21568 128 13983 Y80 C E D K N V P Y V F V R S K A
Sea Urchin Strong. purpuratus XP_792122 127 13896 Y79 C E D K N V P Y V F V R S K E
Poplar Tree Populus trichocarpa XP_002326012 128 13856 Y80 A E D K N V P Y V F V S S K Q
Maize Zea mays NP_001152403 127 13728 Y79 A E D K N V P Y V F V P S K Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEY9 156 16930 Y96 C E E A G V P Y V Y V P S K E
Baker's Yeast Sacchar. cerevisiae P39990 126 13550 Y78 C E D K N V P Y V F V P S R V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47 N.A. N.A. N.A. 29.4 94.5 N.A. 95.3 92.9 92.9 31.3 N.A. 78.1 85.9 77.3 81.2
Protein Similarity: 100 47 N.A. N.A. N.A. 49.6 96 N.A. 96.1 97.6 96 52 N.A. 90.6 93.7 89.8 91.4
P-Site Identity: 100 100 N.A. N.A. N.A. 60 93.3 N.A. 100 100 100 53.3 N.A. 100 100 93.3 93.3
P-Site Similarity: 100 100 N.A. N.A. N.A. 86.6 93.3 N.A. 100 100 100 80 N.A. 100 100 93.3 100
Percent
Protein Identity: 78.9 79.6 N.A. 32 69.5 N.A.
Protein Similarity: 87.5 89.8 N.A. 50.6 85.1 N.A.
P-Site Identity: 86.6 86.6 N.A. 60 80 N.A.
P-Site Similarity: 86.6 86.6 N.A. 80 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 7 0 0 0 0 7 0 0 0 0 0 7 % A
% Cys: 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 94 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 100 7 0 0 0 0 0 0 0 0 0 0 0 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 82 0 0 0 0 0 0 0 0 0 94 0 % K
% Leu: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 88 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 100 0 0 0 0 32 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 63 % Q
% Arg: 0 0 0 7 0 0 0 0 0 0 0 57 0 7 0 % R
% Ser: 0 0 0 0 7 0 0 0 0 0 0 7 100 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % T
% Val: 0 0 0 0 0 88 0 0 94 0 94 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 19 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _