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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPEPPS All Species: 12.12
Human Site: S32 Identified Species: 20.51
UniProt: P55786 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55786 NP_006301.3 919 103276 S32 L L L V F S R S S R R R L H S
Chimpanzee Pan troglodytes XP_001173625 915 102923 S28 F I I F R S R S S R R R L H S
Rhesus Macaque Macaca mulatta XP_001082709 805 90718 T22 V T L S F P S T L Q T G T G T
Dog Lupus familis XP_537659 837 94265 Y25 I D I I T A S Y A P E G D E E
Cat Felis silvestris
Mouse Mus musculus Q11011 920 103333 R33 L L L S R S S R R R R R L H S
Rat Rattus norvegicus Q9JJ22 930 106401 T25 S C C Q N S D T A S P K A S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234986 855 96195 T25 S Q S V K H A T N Q I V M N C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001157499 872 98035 L27 G L R L K P D L V D F T F E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728614 1075 122740 Y163 L G D L C S Q Y R A I L A H T
Honey Bee Apis mellifera XP_394245 867 98542 N28 Y N I V L S P N L K T F V F D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188563 781 87435
Poplar Tree Populus trichocarpa XP_002308539 857 96803 R29 I P K R Y D I R L K P E L T A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_195035 879 98160 I28 L R L N P D L I A C T F T G T
Baker's Yeast Sacchar. cerevisiae P32454 935 105566 C83 F T E T S H A C A K C Q K T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 87.4 90.2 N.A. 97 32.5 N.A. N.A. 84.3 N.A. 80.9 N.A. 47.9 53.5 N.A. 54.3
Protein Similarity: 100 97.7 87.4 90.5 N.A. 98.4 50.9 N.A. N.A. 88.2 N.A. 88 N.A. 61.1 68.5 N.A. 65.5
P-Site Identity: 100 66.6 13.3 0 N.A. 66.6 6.6 N.A. N.A. 6.6 N.A. 6.6 N.A. 20 13.3 N.A. 0
P-Site Similarity: 100 80 40 33.3 N.A. 66.6 33.3 N.A. N.A. 40 N.A. 13.3 N.A. 40 40 N.A. 0
Percent
Protein Identity: 42.7 N.A. N.A. 42.9 35.4 N.A.
Protein Similarity: 58.5 N.A. N.A. 58.9 53.9 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 15 0 29 8 0 0 15 0 8 % A
% Cys: 0 8 8 0 8 0 0 8 0 8 8 0 0 0 8 % C
% Asp: 0 8 8 0 0 15 15 0 0 8 0 0 8 0 8 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 8 8 0 15 8 % E
% Phe: 15 0 0 8 15 0 0 0 0 0 8 15 8 8 0 % F
% Gly: 8 8 0 0 0 0 0 0 0 0 0 15 0 15 8 % G
% His: 0 0 0 0 0 15 0 0 0 0 0 0 0 29 0 % H
% Ile: 15 8 22 8 0 0 8 8 0 0 15 0 0 0 0 % I
% Lys: 0 0 8 0 15 0 0 0 0 22 0 8 8 0 0 % K
% Leu: 29 22 29 15 8 0 8 8 22 0 0 8 29 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 0 8 8 0 0 8 8 0 0 0 0 8 8 % N
% Pro: 0 8 0 0 8 15 8 0 0 8 15 0 0 0 0 % P
% Gln: 0 8 0 8 0 0 8 0 0 15 0 8 0 0 0 % Q
% Arg: 0 8 8 8 15 0 15 15 15 22 22 22 0 0 0 % R
% Ser: 15 0 8 15 8 43 22 15 15 8 0 0 0 8 29 % S
% Thr: 0 15 0 8 8 0 0 22 0 0 22 8 15 15 22 % T
% Val: 8 0 0 22 0 0 0 0 8 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _