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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPPS
All Species:
14.85
Human Site:
S549
Identified Species:
25.13
UniProt:
P55786
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55786
NP_006301.3
919
103276
S549
V
P
I
T
I
S
T
S
E
D
P
N
Q
A
K
Chimpanzee
Pan troglodytes
XP_001173625
915
102923
S545
V
P
I
T
I
S
T
S
E
D
P
N
Q
A
K
Rhesus Macaque
Macaca mulatta
XP_001082709
805
90718
S510
G
L
Q
N
D
L
F
S
L
A
R
A
G
I
I
Dog
Lupus familis
XP_537659
837
94265
A514
Y
R
T
Q
Y
S
S
A
M
L
E
S
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q11011
920
103333
S550
V
P
I
T
I
S
T
S
E
D
P
N
Q
A
K
Rat
Rattus norvegicus
Q9JJ22
930
106401
Y538
V
H
L
K
Q
E
H
Y
M
K
G
S
E
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234986
855
96195
T526
G
T
V
G
F
Y
R
T
Q
Y
S
P
D
M
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157499
872
98035
V523
L
D
Q
P
E
T
T
V
N
I
T
N
V
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728614
1075
122740
S712
V
P
I
S
V
S
T
S
K
N
P
T
G
I
A
Honey Bee
Apis mellifera
XP_394245
867
98542
E518
V
L
K
D
L
L
D
E
K
T
K
E
F
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188563
781
87435
Q486
E
K
F
S
A
D
G
Q
K
E
G
Q
D
M
R
Poplar Tree
Populus trichocarpa
XP_002308539
857
96803
C527
V
K
E
L
L
G
S
C
Q
V
G
S
G
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195035
879
98160
G526
L
G
C
S
I
A
D
G
S
D
K
I
N
G
T
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
G593
L
A
L
K
T
K
N
G
V
D
S
S
V
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
87.4
90.2
N.A.
97
32.5
N.A.
N.A.
84.3
N.A.
80.9
N.A.
47.9
53.5
N.A.
54.3
Protein Similarity:
100
97.7
87.4
90.5
N.A.
98.4
50.9
N.A.
N.A.
88.2
N.A.
88
N.A.
61.1
68.5
N.A.
65.5
P-Site Identity:
100
100
6.6
6.6
N.A.
100
6.6
N.A.
N.A.
0
N.A.
20
N.A.
46.6
6.6
N.A.
0
P-Site Similarity:
100
100
6.6
26.6
N.A.
100
26.6
N.A.
N.A.
20
N.A.
33.3
N.A.
73.3
20
N.A.
26.6
Percent
Protein Identity:
42.7
N.A.
N.A.
42.9
35.4
N.A.
Protein Similarity:
58.5
N.A.
N.A.
58.9
53.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
40
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
8
0
8
0
8
0
29
8
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
8
8
8
15
0
0
36
0
0
15
0
0
% D
% Glu:
8
0
8
0
8
8
0
8
22
8
8
8
8
0
0
% E
% Phe:
0
0
8
0
8
0
8
0
0
0
0
0
8
0
8
% F
% Gly:
15
8
0
8
0
8
8
15
0
0
22
0
22
8
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
29
0
29
0
0
0
0
8
0
8
0
15
8
% I
% Lys:
0
15
8
15
0
8
0
0
22
8
15
0
0
0
22
% K
% Leu:
22
15
15
8
15
15
0
0
8
8
0
0
8
8
15
% L
% Met:
0
0
0
0
0
0
0
0
15
0
0
0
0
15
0
% M
% Asn:
0
0
0
8
0
0
8
0
8
8
0
29
8
0
0
% N
% Pro:
0
29
0
8
0
0
0
0
0
0
29
8
0
0
15
% P
% Gln:
0
0
15
8
8
0
0
8
15
0
0
8
22
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
8
0
0
8
8
% R
% Ser:
0
0
0
22
0
36
15
36
8
0
15
29
0
8
8
% S
% Thr:
0
8
8
22
8
8
36
8
0
8
8
8
0
0
8
% T
% Val:
50
0
8
0
8
0
0
8
8
8
0
0
15
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
8
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _