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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPPS
All Species:
14.85
Human Site:
S684
Identified Species:
25.13
UniProt:
P55786
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55786
NP_006301.3
919
103276
S684
E
F
V
K
D
V
F
S
P
I
G
E
R
L
G
Chimpanzee
Pan troglodytes
XP_001173625
915
102923
S680
E
F
V
K
D
V
F
S
P
I
G
E
R
L
G
Rhesus Macaque
Macaca mulatta
XP_001082709
805
90718
Q623
K
D
H
V
E
G
K
Q
I
L
S
A
D
L
R
Dog
Lupus familis
XP_537659
837
94265
V627
D
A
L
L
R
G
L
V
L
G
K
L
G
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q11011
920
103333
S685
E
F
V
K
D
V
F
S
P
I
G
E
R
L
G
Rat
Rattus norvegicus
Q9JJ22
930
106401
E658
L
Y
L
K
N
E
T
E
I
M
P
I
F
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234986
855
96195
L639
G
E
G
H
L
D
A
L
L
R
G
L
V
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157499
872
98035
T639
E
F
I
R
D
L
F
T
P
I
G
M
K
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728614
1075
122740
E847
R
F
G
R
N
L
Y
E
P
V
A
Y
R
L
G
Honey Bee
Apis mellifera
XP_394245
867
98542
R639
A
F
G
R
N
L
M
R
D
I
T
D
K
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188563
781
87435
N599
K
L
F
E
A
F
E
N
E
T
D
Y
T
V
W
Poplar Tree
Populus trichocarpa
XP_002308539
857
96803
S641
P
D
Q
D
P
F
S
S
Q
I
S
S
K
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195035
879
98160
V642
I
K
H
F
F
I
G
V
F
Q
F
A
A
G
K
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
L741
D
S
F
S
T
Q
R
L
K
V
T
M
F
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
87.4
90.2
N.A.
97
32.5
N.A.
N.A.
84.3
N.A.
80.9
N.A.
47.9
53.5
N.A.
54.3
Protein Similarity:
100
97.7
87.4
90.5
N.A.
98.4
50.9
N.A.
N.A.
88.2
N.A.
88
N.A.
61.1
68.5
N.A.
65.5
P-Site Identity:
100
100
6.6
0
N.A.
100
13.3
N.A.
N.A.
20
N.A.
60
N.A.
33.3
26.6
N.A.
0
P-Site Similarity:
100
100
26.6
13.3
N.A.
100
40
N.A.
N.A.
20
N.A.
93.3
N.A.
66.6
60
N.A.
26.6
Percent
Protein Identity:
42.7
N.A.
N.A.
42.9
35.4
N.A.
Protein Similarity:
58.5
N.A.
N.A.
58.9
53.9
N.A.
P-Site Identity:
26.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
8
0
0
0
8
15
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
15
0
8
29
8
0
0
8
0
8
8
8
0
0
% D
% Glu:
29
8
0
8
8
8
8
15
8
0
0
22
0
0
0
% E
% Phe:
0
43
15
8
8
15
29
0
8
0
8
0
15
0
0
% F
% Gly:
8
0
22
0
0
15
8
0
0
8
36
0
8
15
65
% G
% His:
0
0
15
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
8
0
0
15
43
0
8
0
0
0
% I
% Lys:
15
8
0
29
0
0
8
0
8
0
8
0
22
8
8
% K
% Leu:
8
8
15
8
8
22
8
15
15
8
0
15
0
65
0
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
15
0
0
0
% M
% Asn:
0
0
0
0
22
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
36
0
8
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
8
8
8
0
0
0
8
0
% Q
% Arg:
8
0
0
22
8
0
8
8
0
8
0
0
29
0
8
% R
% Ser:
0
8
0
8
0
0
8
29
0
0
15
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
8
8
0
8
15
0
8
0
0
% T
% Val:
0
0
22
8
0
22
0
15
0
15
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _