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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPPS
All Species:
11.82
Human Site:
T166
Identified Species:
20
UniProt:
P55786
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55786
NP_006301.3
919
103276
T166
F
Y
R
S
K
Y
T
T
P
S
G
E
V
R
Y
Chimpanzee
Pan troglodytes
XP_001173625
915
102923
T162
F
Y
R
S
K
Y
T
T
P
S
G
E
V
R
Y
Rhesus Macaque
Macaca mulatta
XP_001082709
805
90718
G149
V
E
T
R
S
K
D
G
V
C
V
R
V
Y
T
Dog
Lupus familis
XP_537659
837
94265
F153
E
N
V
V
E
V
K
F
A
R
T
P
V
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q11011
920
103333
T167
F
Y
R
S
R
Y
T
T
P
A
G
E
V
R
Y
Rat
Rattus norvegicus
Q9JJ22
930
106401
T158
F
Y
K
S
T
Y
R
T
Q
E
G
E
R
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234986
855
96195
D162
D
R
K
P
Y
P
D
D
E
N
L
V
E
V
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157499
872
98035
I157
A
I
K
A
T
F
D
I
T
L
I
V
P
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728614
1075
122740
G331
F
Y
R
S
K
Y
F
G
P
N
G
E
E
R
F
Honey Bee
Apis mellifera
XP_394245
867
98542
K156
C
W
D
E
P
A
H
K
A
T
F
D
I
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188563
781
87435
E125
K
Y
T
T
P
A
G
E
E
R
Y
C
A
V
T
Poplar Tree
Populus trichocarpa
XP_002308539
857
96803
E156
R
C
F
P
C
W
D
E
P
V
C
K
A
T
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195035
879
98160
K155
C
W
D
E
P
A
C
K
A
T
F
K
I
T
L
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
D213
F
Y
R
A
K
Y
E
D
K
L
T
G
E
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
87.4
90.2
N.A.
97
32.5
N.A.
N.A.
84.3
N.A.
80.9
N.A.
47.9
53.5
N.A.
54.3
Protein Similarity:
100
97.7
87.4
90.5
N.A.
98.4
50.9
N.A.
N.A.
88.2
N.A.
88
N.A.
61.1
68.5
N.A.
65.5
P-Site Identity:
100
100
6.6
6.6
N.A.
86.6
53.3
N.A.
N.A.
0
N.A.
0
N.A.
66.6
0
N.A.
6.6
P-Site Similarity:
100
100
6.6
13.3
N.A.
100
60
N.A.
N.A.
13.3
N.A.
26.6
N.A.
80
26.6
N.A.
13.3
Percent
Protein Identity:
42.7
N.A.
N.A.
42.9
35.4
N.A.
Protein Similarity:
58.5
N.A.
N.A.
58.9
53.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
0
22
0
0
22
8
0
0
15
0
0
% A
% Cys:
15
8
0
0
8
0
8
0
0
8
8
8
0
0
0
% C
% Asp:
8
0
15
0
0
0
29
15
0
0
0
8
0
0
8
% D
% Glu:
8
8
0
15
8
0
8
15
15
8
0
36
22
0
0
% E
% Phe:
43
0
8
0
0
8
8
8
0
0
15
0
0
0
15
% F
% Gly:
0
0
0
0
0
0
8
15
0
0
36
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
8
0
15
0
8
% I
% Lys:
8
0
22
0
29
8
8
15
8
0
0
15
0
8
15
% K
% Leu:
0
0
0
0
0
0
0
0
0
15
8
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
0
0
0
15
22
8
0
0
36
0
0
8
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
8
36
8
8
0
8
0
0
15
0
8
8
36
0
% R
% Ser:
0
0
0
36
8
0
0
0
0
15
0
0
0
0
8
% S
% Thr:
0
0
15
8
15
0
22
29
8
15
15
0
0
29
15
% T
% Val:
8
0
8
8
0
8
0
0
8
8
8
15
36
15
0
% V
% Trp:
0
15
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
8
43
0
0
0
0
8
0
0
8
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _