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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPPS
All Species:
24.85
Human Site:
T650
Identified Species:
42.05
UniProt:
P55786
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55786
NP_006301.3
919
103276
T650
F
V
N
E
P
N
Y
T
V
W
S
D
L
S
C
Chimpanzee
Pan troglodytes
XP_001173625
915
102923
T646
F
V
N
E
P
N
Y
T
V
W
S
D
L
S
C
Rhesus Macaque
Macaca mulatta
XP_001082709
805
90718
A589
P
G
E
G
H
L
D
A
L
L
R
G
L
V
L
Dog
Lupus familis
XP_537659
837
94265
I593
H
T
D
F
Y
E
E
I
Q
E
F
V
K
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q11011
920
103333
T651
F
V
N
E
P
N
Y
T
V
W
S
D
L
S
C
Rat
Rattus norvegicus
Q9JJ22
930
106401
D624
H
T
T
I
S
S
N
D
R
A
S
L
I
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234986
855
96195
D605
S
T
L
L
S
H
T
D
F
Y
E
E
I
Q
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157499
872
98035
T605
F
V
N
E
P
N
Y
T
V
W
S
D
L
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728614
1075
122740
T813
Y
R
N
E
T
N
Y
T
V
W
T
A
I
T
N
Honey Bee
Apis mellifera
XP_394245
867
98542
T605
F
Q
H
E
D
N
F
T
V
W
S
S
I
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188563
781
87435
P565
G
I
R
D
Q
V
L
P
A
R
D
R
L
G
L
Poplar Tree
Populus trichocarpa
XP_002308539
857
96803
I607
Y
R
E
E
L
E
Y
I
V
L
S
N
L
I
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195035
879
98160
T608
Y
K
K
E
L
D
Y
T
V
L
S
N
L
I
A
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
T707
W
L
F
E
P
K
E
T
Q
D
A
L
D
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
87.4
90.2
N.A.
97
32.5
N.A.
N.A.
84.3
N.A.
80.9
N.A.
47.9
53.5
N.A.
54.3
Protein Similarity:
100
97.7
87.4
90.5
N.A.
98.4
50.9
N.A.
N.A.
88.2
N.A.
88
N.A.
61.1
68.5
N.A.
65.5
P-Site Identity:
100
100
6.6
0
N.A.
100
6.6
N.A.
N.A.
0
N.A.
100
N.A.
46.6
46.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
6.6
N.A.
100
26.6
N.A.
N.A.
26.6
N.A.
100
N.A.
73.3
66.6
N.A.
20
Percent
Protein Identity:
42.7
N.A.
N.A.
42.9
35.4
N.A.
Protein Similarity:
58.5
N.A.
N.A.
58.9
53.9
N.A.
P-Site Identity:
33.3
N.A.
N.A.
40
20
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
8
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% C
% Asp:
0
0
8
8
8
8
8
15
0
8
8
29
8
8
0
% D
% Glu:
0
0
15
65
0
15
15
0
0
8
8
8
0
0
0
% E
% Phe:
36
0
8
8
0
0
8
0
8
0
8
0
0
0
8
% F
% Gly:
8
8
0
8
0
0
0
0
0
0
0
8
0
8
0
% G
% His:
15
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
15
0
0
0
0
29
15
0
% I
% Lys:
0
8
8
0
0
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
8
8
8
15
8
8
0
8
22
0
15
58
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
36
0
0
43
8
0
0
0
0
15
0
15
29
% N
% Pro:
8
0
0
0
36
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
0
0
0
15
0
0
0
0
8
0
% Q
% Arg:
0
15
8
0
0
0
0
0
8
8
8
8
0
0
0
% R
% Ser:
8
0
0
0
15
8
0
0
0
0
58
8
0
29
0
% S
% Thr:
0
22
8
0
8
0
8
58
0
0
8
0
0
8
0
% T
% Val:
0
29
0
0
0
8
0
0
58
0
0
8
0
15
15
% V
% Trp:
8
0
0
0
0
0
0
0
0
43
0
0
0
0
0
% W
% Tyr:
22
0
0
0
8
0
50
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _