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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPPS
All Species:
18.79
Human Site:
Y451
Identified Species:
31.79
UniProt:
P55786
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55786
NP_006301.3
919
103276
Y451
V
I
R
M
L
H
D
Y
I
G
D
K
D
F
K
Chimpanzee
Pan troglodytes
XP_001173625
915
102923
Y447
V
I
R
M
L
H
D
Y
I
G
D
K
D
F
K
Rhesus Macaque
Macaca mulatta
XP_001082709
805
90718
F412
L
R
L
S
Q
K
K
F
C
A
G
G
S
Y
V
Dog
Lupus familis
XP_537659
837
94265
T416
A
A
V
M
N
T
W
T
K
Q
M
G
F
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q11011
920
103333
Y452
V
I
R
M
L
H
D
Y
I
G
D
K
D
F
K
Rat
Rattus norvegicus
Q9JJ22
930
106401
Y440
I
L
N
M
L
R
D
Y
L
S
A
D
T
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234986
855
96195
V428
S
G
K
P
I
A
A
V
M
N
T
W
T
K
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157499
872
98035
H425
A
Y
L
L
K
F
Q
H
K
N
A
S
T
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728614
1075
122740
Y614
V
I
R
M
L
H
D
Y
I
G
E
D
T
F
R
Honey Bee
Apis mellifera
XP_394245
867
98542
Y420
F
R
K
G
M
N
L
Y
L
K
K
H
S
Y
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188563
781
87435
F388
P
D
E
V
D
E
I
F
D
L
I
S
Y
C
K
Poplar Tree
Populus trichocarpa
XP_002308539
857
96803
Y429
S
Y
I
K
K
H
A
Y
S
N
A
K
T
E
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195035
879
98160
K428
N
H
A
Y
S
N
A
K
T
E
D
L
W
A
A
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
W495
L
L
R
M
I
S
K
W
L
G
E
E
T
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
87.4
90.2
N.A.
97
32.5
N.A.
N.A.
84.3
N.A.
80.9
N.A.
47.9
53.5
N.A.
54.3
Protein Similarity:
100
97.7
87.4
90.5
N.A.
98.4
50.9
N.A.
N.A.
88.2
N.A.
88
N.A.
61.1
68.5
N.A.
65.5
P-Site Identity:
100
100
0
6.6
N.A.
100
40
N.A.
N.A.
0
N.A.
0
N.A.
73.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
20
6.6
N.A.
100
60
N.A.
N.A.
26.6
N.A.
13.3
N.A.
86.6
40
N.A.
20
Percent
Protein Identity:
42.7
N.A.
N.A.
42.9
35.4
N.A.
Protein Similarity:
58.5
N.A.
N.A.
58.9
53.9
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
0
0
8
22
0
0
8
22
0
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
8
0
36
0
8
0
29
15
22
0
15
% D
% Glu:
0
0
8
0
0
8
0
0
0
8
15
8
0
15
0
% E
% Phe:
8
0
0
0
0
8
0
15
0
0
0
0
8
43
0
% F
% Gly:
0
8
0
8
0
0
0
0
0
36
8
15
0
0
0
% G
% His:
0
8
0
0
0
36
0
8
0
0
0
8
0
0
0
% H
% Ile:
8
29
8
0
15
0
8
0
29
0
8
0
0
0
8
% I
% Lys:
0
0
15
8
15
8
15
8
15
8
8
29
0
8
36
% K
% Leu:
15
15
15
8
36
0
8
0
22
8
0
8
0
0
8
% L
% Met:
0
0
0
50
8
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
8
0
8
0
8
15
0
0
0
22
0
0
0
0
0
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
8
0
0
0
0
8
% Q
% Arg:
0
15
36
0
0
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
15
0
0
8
8
8
0
0
8
8
0
15
15
0
0
% S
% Thr:
0
0
0
0
0
8
0
8
8
0
8
0
43
0
0
% T
% Val:
29
0
8
8
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
8
0
0
0
8
8
0
0
% W
% Tyr:
0
15
0
8
0
0
0
50
0
0
0
0
8
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _