KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPPS
All Species:
18.79
Human Site:
Y464
Identified Species:
31.79
UniProt:
P55786
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55786
NP_006301.3
919
103276
Y464
F
K
K
G
M
N
M
Y
L
T
K
F
Q
Q
K
Chimpanzee
Pan troglodytes
XP_001173625
915
102923
Y460
F
K
K
G
M
N
M
Y
L
T
K
F
Q
Q
K
Rhesus Macaque
Macaca mulatta
XP_001082709
805
90718
Q425
Y
V
G
E
D
C
P
Q
W
M
V
P
I
T
I
Dog
Lupus familis
XP_537659
837
94265
E429
P
L
I
Y
V
E
A
E
Q
V
E
D
D
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q11011
920
103333
Y465
F
K
K
G
M
N
M
Y
L
T
K
F
Q
Q
K
Rat
Rattus norvegicus
Q9JJ22
930
106401
Y453
F
K
R
G
I
V
Q
Y
L
Q
K
Y
S
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234986
855
96195
I441
K
Q
M
G
F
P
L
I
Y
V
E
A
E
Q
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157499
872
98035
E438
E
D
L
W
E
C
L
E
Q
A
S
G
K
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728614
1075
122740
Y627
F
R
K
G
M
N
L
Y
L
T
R
H
Q
Y
G
Honey Bee
Apis mellifera
XP_394245
867
98542
D433
Y
A
N
A
E
T
G
D
L
W
D
A
L
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188563
781
87435
R401
C
K
G
A
S
V
I
R
M
L
H
D
F
I
G
Poplar Tree
Populus trichocarpa
XP_002308539
857
96803
E442
E
D
L
W
A
A
L
E
E
G
S
G
E
P
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195035
879
98160
G441
A
A
L
E
A
G
S
G
E
P
V
N
K
L
M
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
Y508
F
I
K
G
V
S
Q
Y
L
N
K
F
K
Y
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
87.4
90.2
N.A.
97
32.5
N.A.
N.A.
84.3
N.A.
80.9
N.A.
47.9
53.5
N.A.
54.3
Protein Similarity:
100
97.7
87.4
90.5
N.A.
98.4
50.9
N.A.
N.A.
88.2
N.A.
88
N.A.
61.1
68.5
N.A.
65.5
P-Site Identity:
100
100
0
0
N.A.
100
46.6
N.A.
N.A.
13.3
N.A.
0
N.A.
60
6.6
N.A.
6.6
P-Site Similarity:
100
100
6.6
20
N.A.
100
66.6
N.A.
N.A.
46.6
N.A.
13.3
N.A.
80
26.6
N.A.
20
Percent
Protein Identity:
42.7
N.A.
N.A.
42.9
35.4
N.A.
Protein Similarity:
58.5
N.A.
N.A.
58.9
53.9
N.A.
P-Site Identity:
0
N.A.
N.A.
0
46.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
6.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
15
15
8
8
0
0
8
0
15
0
0
0
% A
% Cys:
8
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
8
0
0
8
0
0
8
15
8
0
0
% D
% Glu:
15
0
0
15
15
8
0
22
15
0
15
0
15
8
8
% E
% Phe:
43
0
0
0
8
0
0
0
0
0
0
29
8
0
0
% F
% Gly:
0
0
15
50
0
8
8
8
0
8
0
15
0
0
22
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
8
8
0
8
0
8
8
0
0
0
0
8
8
15
% I
% Lys:
8
36
36
0
0
0
0
0
0
0
36
0
22
0
29
% K
% Leu:
0
8
22
0
0
0
29
0
50
8
0
0
8
8
8
% L
% Met:
0
0
8
0
29
0
22
0
8
8
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
29
0
0
0
8
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
8
8
0
0
8
0
8
0
15
0
% P
% Gln:
0
8
0
0
0
0
15
8
15
8
0
0
29
29
8
% Q
% Arg:
0
8
8
0
0
0
0
8
0
0
8
0
0
8
0
% R
% Ser:
0
0
0
0
8
8
8
0
0
0
15
0
8
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
29
0
0
0
8
0
% T
% Val:
0
8
0
0
15
15
0
0
0
15
15
0
0
0
8
% V
% Trp:
0
0
0
15
0
0
0
0
8
8
0
0
0
0
0
% W
% Tyr:
15
0
0
8
0
0
0
43
8
0
0
8
0
22
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _