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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPPS
All Species:
30
Human Site:
Y842
Identified Species:
50.77
UniProt:
P55786
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55786
NP_006301.3
919
103276
Y842
W
E
E
L
Y
N
R
Y
Q
G
G
F
L
I
S
Chimpanzee
Pan troglodytes
XP_001173625
915
102923
Y838
W
E
E
L
Y
N
R
Y
Q
G
G
F
L
I
S
Rhesus Macaque
Macaca mulatta
XP_001082709
805
90718
K739
F
L
I
S
R
L
I
K
L
S
V
E
G
F
A
Dog
Lupus familis
XP_537659
837
94265
Y760
W
E
E
L
Y
N
R
Y
Q
G
G
F
L
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q11011
920
103333
Y843
W
E
E
L
H
N
R
Y
Q
G
G
F
L
I
S
Rat
Rattus norvegicus
Q9JJ22
930
106401
F853
W
N
K
I
V
Q
K
F
E
L
G
S
S
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234986
855
96195
Y777
W
E
E
L
Y
N
R
Y
Q
G
G
F
L
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157499
872
98035
Y797
W
E
E
L
H
N
R
Y
Q
G
G
F
L
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728614
1075
122740
Y1004
N
K
Q
L
L
E
R
Y
Q
G
G
F
L
L
S
Honey Bee
Apis mellifera
XP_394245
867
98542
Y796
W
K
T
L
L
D
R
Y
G
G
G
F
L
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188563
781
87435
N715
H
G
D
E
D
T
L
N
D
M
I
E
S
C
T
Poplar Tree
Populus trichocarpa
XP_002308539
857
96803
A771
S
E
V
R
S
Q
D
A
V
F
G
L
A
V
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195035
879
98160
W804
W
E
Y
I
G
N
T
W
G
S
G
F
L
I
T
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
V867
V
E
A
L
W
N
W
V
K
K
N
W
D
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
87.4
90.2
N.A.
97
32.5
N.A.
N.A.
84.3
N.A.
80.9
N.A.
47.9
53.5
N.A.
54.3
Protein Similarity:
100
97.7
87.4
90.5
N.A.
98.4
50.9
N.A.
N.A.
88.2
N.A.
88
N.A.
61.1
68.5
N.A.
65.5
P-Site Identity:
100
100
0
100
N.A.
93.3
13.3
N.A.
N.A.
100
N.A.
93.3
N.A.
60
66.6
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
100
46.6
N.A.
N.A.
100
N.A.
100
N.A.
80
80
N.A.
13.3
Percent
Protein Identity:
42.7
N.A.
N.A.
42.9
35.4
N.A.
Protein Similarity:
58.5
N.A.
N.A.
58.9
53.9
N.A.
P-Site Identity:
20
N.A.
N.A.
46.6
20
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
66.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
8
8
8
0
8
0
0
0
8
0
0
% D
% Glu:
0
65
43
8
0
8
0
0
8
0
0
15
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
8
0
65
0
8
0
% F
% Gly:
0
8
0
0
8
0
0
0
15
58
79
0
8
0
0
% G
% His:
8
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
15
0
0
8
0
0
0
8
0
0
58
8
% I
% Lys:
0
15
8
0
0
0
8
8
8
8
0
0
0
0
0
% K
% Leu:
0
8
0
65
15
8
8
0
8
8
0
8
65
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
58
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
15
0
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
0
58
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
8
0
0
0
0
15
0
8
15
8
65
% S
% Thr:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
15
% T
% Val:
8
0
8
0
8
0
0
8
8
0
8
0
0
8
0
% V
% Trp:
65
0
0
0
8
0
8
8
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
0
29
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _