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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNRNPH2
All Species:
18.18
Human Site:
S186
Identified Species:
44.44
UniProt:
P55795
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55795
NP_001027565.1
449
49264
S186
R
Y
I
E
I
F
K
S
S
R
A
E
V
R
T
Chimpanzee
Pan troglodytes
XP_001150324
472
51229
S186
R
Y
I
E
I
F
K
S
S
R
A
E
V
R
T
Rhesus Macaque
Macaca mulatta
XP_001094194
425
46654
K170
E
I
A
E
K
A
L
K
K
H
K
E
R
I
G
Dog
Lupus familis
XP_538110
449
49261
S186
R
Y
I
E
I
F
K
S
S
R
A
E
V
R
T
Cat
Felis silvestris
Mouse
Mus musculus
P70333
449
49261
S186
R
Y
I
E
I
F
K
S
S
R
A
E
V
R
T
Rat
Rattus norvegicus
Q6AY09
449
49275
S186
R
Y
I
E
I
F
K
S
S
R
A
E
V
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLR4
701
76929
L344
T
A
T
Q
E
D
V
L
G
F
L
G
P
E
C
Frog
Xenopus laevis
Q7ZY29
688
76408
V343
F
T
A
T
A
E
E
V
L
A
F
F
G
Q
Q
Zebra Danio
Brachydanio rerio
A1L1G1
714
78118
G311
D
F
L
K
I
A
G
G
T
S
N
E
V
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
R286
N
A
I
I
V
R
M
R
G
L
P
Y
D
C
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.4
94.6
99.5
N.A.
99.1
98.8
N.A.
N.A.
21.8
20.3
23.2
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
100
91.9
94.6
99.7
N.A.
99.7
99.5
N.A.
N.A.
35.8
35.3
35.2
N.A.
N.A.
N.A.
34.1
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
0
0
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
6.6
13.3
53.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
20
0
10
20
0
0
0
10
50
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% C
% Asp:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% D
% Glu:
10
0
0
60
10
10
10
0
0
0
0
70
0
10
0
% E
% Phe:
10
10
0
0
0
50
0
0
0
10
10
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
10
20
0
0
10
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
10
60
10
60
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
10
10
0
50
10
10
0
10
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
10
10
10
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
50
0
0
0
0
10
0
10
0
50
0
0
10
50
0
% R
% Ser:
0
0
0
0
0
0
0
50
50
10
0
0
0
0
10
% S
% Thr:
10
10
10
10
0
0
0
0
10
0
0
0
0
0
60
% T
% Val:
0
0
0
0
10
0
10
10
0
0
0
0
60
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _