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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SH3BGR All Species: 3.94
Human Site: S20 Identified Species: 9.63
UniProt: P55822 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55822 NP_001001713.1 239 26086 S20 K L E R D C R S P V D P W A A
Chimpanzee Pan troglodytes XP_514900 402 44614 I154 F G C N V L R I L L P S F S S
Rhesus Macaque Macaca mulatta XP_001118709 218 23871 S20 K L E R E G R S S V E P W A A
Dog Lupus familis XP_544890 317 34194 A92 A L G G R Q L A P G T C T C T
Cat Felis silvestris
Mouse Mus musculus Q9WUZ7 214 23084 E22 A I R K K Q Q E V V G F L E A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519197 122 13752
Chicken Gallus gallus XP_416732 181 20408 K18 S G S T A I K K K Q Q E V V G
Frog Xenopus laevis Q3KPU0 106 12454
Zebra Danio Brachydanio rerio Q6GMK7 105 12112
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NFP5 158 17470
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.7 83.2 48.9 N.A. 24.2 N.A. N.A. 32.2 53.1 25.1 25.5 N.A. 25.1 N.A. N.A. N.A.
Protein Similarity: 100 53.4 86.1 54.2 N.A. 35.5 N.A. N.A. 41.4 60.6 35.1 35.9 N.A. 43 N.A. N.A. N.A.
P-Site Identity: 100 6.6 73.3 13.3 N.A. 13.3 N.A. N.A. 0 0 0 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 86.6 20 N.A. 33.3 N.A. N.A. 0 6.6 0 0 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 10 0 0 10 0 0 0 0 0 20 30 % A
% Cys: 0 0 10 0 0 10 0 0 0 0 0 10 0 10 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 20 0 10 0 0 10 0 0 10 10 0 10 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % F
% Gly: 0 20 10 10 0 10 0 0 0 10 10 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 20 0 0 10 10 0 10 10 10 0 0 0 0 0 0 % K
% Leu: 0 30 0 0 0 10 10 0 10 10 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 20 0 10 20 0 0 0 % P
% Gln: 0 0 0 0 0 20 10 0 0 10 10 0 0 0 0 % Q
% Arg: 0 0 10 20 10 0 30 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 0 0 0 0 20 10 0 0 10 0 10 10 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 10 0 10 0 10 % T
% Val: 0 0 0 0 10 0 0 0 10 30 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _