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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3BGR
All Species:
9.09
Human Site:
Y138
Identified Species:
22.22
UniProt:
P55822
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55822
NP_001001713.1
239
26086
Y138
Q
I
F
N
E
E
Q
Y
C
G
D
F
D
S
F
Chimpanzee
Pan troglodytes
XP_514900
402
44614
Y300
Q
I
F
N
E
E
Q
Y
C
G
D
F
D
S
F
Rhesus Macaque
Macaca mulatta
XP_001118709
218
23871
I102
I
D
F
K
E
L
D
I
A
G
D
E
D
N
R
Dog
Lupus familis
XP_544890
317
34194
Y210
Q
I
F
N
E
E
Q
Y
C
G
D
F
D
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUZ7
214
23084
P99
Y
S
F
L
G
L
A
P
P
P
G
S
K
V
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519197
122
13752
Q29
A
A
I
K
K
K
Q
Q
D
V
L
G
F
L
E
Chicken
Gallus gallus
XP_416732
181
20408
E88
S
F
F
S
A
K
E
E
N
I
I
Y
S
F
L
Frog
Xenopus laevis
Q3KPU0
106
12454
S12
V
F
L
A
S
S
S
S
S
V
T
I
K
K
R
Zebra Danio
Brachydanio rerio
Q6GMK7
105
12112
G12
V
Y
I
A
S
S
S
G
S
V
A
V
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFP5
158
17470
P65
N
G
G
T
V
S
D
P
E
P
R
H
P
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
83.2
48.9
N.A.
24.2
N.A.
N.A.
32.2
53.1
25.1
25.5
N.A.
25.1
N.A.
N.A.
N.A.
Protein Similarity:
100
53.4
86.1
54.2
N.A.
35.5
N.A.
N.A.
41.4
60.6
35.1
35.9
N.A.
43
N.A.
N.A.
N.A.
P-Site Identity:
100
100
33.3
100
N.A.
6.6
N.A.
N.A.
6.6
6.6
0
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
6.6
N.A.
N.A.
20
33.3
0
0
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
20
10
0
10
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
20
0
10
0
40
0
40
0
0
% D
% Glu:
0
0
0
0
40
30
10
10
10
0
0
10
0
0
10
% E
% Phe:
0
20
60
0
0
0
0
0
0
0
0
30
10
10
30
% F
% Gly:
0
10
10
0
10
0
0
10
0
40
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
30
20
0
0
0
0
10
0
10
10
10
0
0
0
% I
% Lys:
0
0
0
20
10
20
0
0
0
0
0
0
30
20
0
% K
% Leu:
0
0
10
10
0
20
0
0
0
0
10
0
0
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
30
0
0
0
0
10
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
20
10
20
0
0
10
0
10
% P
% Gln:
30
0
0
0
0
0
40
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
30
% R
% Ser:
10
10
0
10
20
30
20
10
20
0
0
10
10
30
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
10
% T
% Val:
20
0
0
0
10
0
0
0
0
30
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
30
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _