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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UCP2 All Species: 21.21
Human Site: T159 Identified Species: 46.67
UniProt: P55851 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55851 NP_003346.2 309 33229 T159 G G R R Y Q S T V N A Y K T I
Chimpanzee Pan troglodytes XP_508635 309 33226 T159 G G R R Y Q S T V N A Y R T I
Rhesus Macaque Macaca mulatta XP_001115559 309 33032 T159 G G R R Y Q S T V D A Y K T I
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P70406 309 33355 T159 G G R R Y Q S T V E A Y K T I
Rat Rattus norvegicus P56500 309 33358 T159 G G R R Y Q S T V E A Y K T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512584 273 28951 C125 E S R Y I V G C T T G A L A V
Chicken Gallus gallus NP_989438 307 33112 R155 G A L P E S N R R Y S G T V D
Frog Xenopus laevis Q6GQ22 291 32540 G143 A Q G N V M Q G G M I V N F I
Zebra Danio Brachydanio rerio Q9W720 310 33554 T160 A S K R Y H S T M D A Y R T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001185598 317 34608 R167 V L N G A P K R Y T G A L N A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06143 298 32973 A150 K R R N Y K N A I D G V Y K I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.7 N.A. N.A. 96.1 95.4 N.A. 73.7 70.8 35.9 80.3 N.A. N.A. N.A. N.A. 61.5
Protein Similarity: 100 99.6 99 N.A. N.A. 96.7 96.1 N.A. 77.3 82.1 52.7 88.7 N.A. N.A. N.A. N.A. 72.8
P-Site Identity: 100 93.3 93.3 N.A. N.A. 93.3 93.3 N.A. 6.6 6.6 6.6 53.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. 13.3 20 6.6 80 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 0 10 0 0 10 0 0 55 19 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 10 % D
% Glu: 10 0 0 0 10 0 0 0 0 19 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 55 46 10 10 0 0 10 10 10 0 28 10 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 10 0 10 0 0 0 73 % I
% Lys: 10 0 10 0 0 10 10 0 0 0 0 0 37 10 0 % K
% Leu: 0 10 10 0 0 0 0 0 0 0 0 0 19 0 0 % L
% Met: 0 0 0 0 0 10 0 0 10 10 0 0 0 0 0 % M
% Asn: 0 0 10 19 0 0 19 0 0 19 0 0 10 10 0 % N
% Pro: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 46 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 64 55 0 0 0 19 10 0 0 0 19 0 0 % R
% Ser: 0 19 0 0 0 10 55 0 0 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 55 10 19 0 0 10 55 0 % T
% Val: 10 0 0 0 10 10 0 0 46 0 0 19 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 64 0 0 0 10 10 0 55 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _