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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UCP2 All Species: 21.82
Human Site: Y59 Identified Species: 48
UniProt: P55851 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55851 NP_003346.2 309 33229 Y59 R A T A S A Q Y R G V M G T I
Chimpanzee Pan troglodytes XP_508635 309 33226 Y59 R A T A S A Q Y R G V M G T I
Rhesus Macaque Macaca mulatta XP_001115559 309 33032 Y59 H A T A G A Q Y R G V L G T I
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P70406 309 33355 Y59 R T A A S A Q Y R G V L G T I
Rat Rattus norvegicus P56500 309 33358 Y59 R T A A S A Q Y R G V L G T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512584 273 28951 L29 T A A C I A D L I T F P L D T
Chicken Gallus gallus NP_989438 307 33112 R59 S T N T V E Y R G V L G T L S
Frog Xenopus laevis Q6GQ22 291 32540 I47 N D A K Y K E I R Y R G M M H
Zebra Danio Brachydanio rerio Q9W720 310 33554 Y60 M G R G P V K Y R G V F G T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001185598 317 34608 Y69 E L R A S F R Y R G V F G T I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06143 298 32973 M54 P K P T L F R M L E S I L A N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.7 N.A. N.A. 96.1 95.4 N.A. 73.7 70.8 35.9 80.3 N.A. N.A. N.A. N.A. 61.5
Protein Similarity: 100 99.6 99 N.A. N.A. 96.7 96.1 N.A. 77.3 82.1 52.7 88.7 N.A. N.A. N.A. N.A. 72.8
P-Site Identity: 100 100 80 N.A. N.A. 80 80 N.A. 13.3 0 6.6 46.6 N.A. N.A. N.A. N.A. 60
P-Site Similarity: 100 100 86.6 N.A. N.A. 86.6 86.6 N.A. 13.3 6.6 13.3 53.3 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 37 37 55 0 55 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 10 0 0 0 0 0 0 10 0 % D
% Glu: 10 0 0 0 0 10 10 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 19 0 0 0 0 10 19 0 0 0 % F
% Gly: 0 10 0 10 10 0 0 0 10 64 0 19 64 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 10 0 0 10 10 0 0 10 0 0 64 % I
% Lys: 0 10 0 10 0 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 10 0 0 10 10 0 10 28 19 10 0 % L
% Met: 10 0 0 0 0 0 0 10 0 0 0 19 10 10 0 % M
% Asn: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 10 0 10 0 10 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 46 0 0 0 0 0 0 0 0 % Q
% Arg: 37 0 19 0 0 0 19 10 73 0 10 0 0 0 0 % R
% Ser: 10 0 0 0 46 0 0 0 0 0 10 0 0 0 10 % S
% Thr: 10 28 28 19 0 0 0 0 0 10 0 0 10 64 10 % T
% Val: 0 0 0 0 10 10 0 0 0 10 64 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 64 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _