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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3B
All Species:
1.52
Human Site:
S117
Identified Species:
2.22
UniProt:
P55884
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55884
NP_001032360.1
814
92482
S117
E
Q
A
R
D
E
R
S
D
S
R
A
Q
A
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086876
814
92439
A117
E
R
A
R
D
E
C
A
D
S
R
A
Q
A
A
Dog
Lupus familis
XP_850719
751
86022
A71
E
Q
A
G
D
A
A
A
E
A
R
S
E
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ9
803
91352
A106
A
E
A
V
G
E
Q
A
R
G
H
P
S
A
G
Rat
Rattus norvegicus
Q4G061
797
90892
A106
E
Q
A
R
H
P
S
A
R
A
E
E
E
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513573
692
80444
N69
D
S
V
I
V
V
D
N
V
P
Q
V
G
P
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q569Z1
688
80237
P69
V
I
V
V
D
N
V
P
Q
V
G
P
D
R
L
Zebra Danio
Brachydanio rerio
XP_001335480
681
79630
R67
V
P
Q
V
G
P
D
R
L
E
K
L
K
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q0E940
690
80423
V70
N
I
P
K
V
E
P
V
R
L
E
K
L
K
L
Honey Bee
Apis mellifera
XP_393588
702
81532
D69
V
E
S
V
I
V
I
D
G
V
P
Q
V
E
P
Nematode Worm
Caenorhab. elegans
Q9XWI6
725
83129
L75
L
K
K
V
L
E
R
L
D
P
A
V
K
L
Y
Sea Urchin
Strong. purpuratus
XP_001190551
703
81690
S70
K
E
A
L
G
I
D
S
V
I
V
I
D
N
I
Poplar Tree
Populus trichocarpa
XP_002308719
719
82814
V69
V
V
D
N
L
P
V
V
P
K
E
K
F
D
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z1
712
81857
E69
H
L
P
V
V
P
K
E
K
F
E
K
L
E
G
Baker's Yeast
Sacchar. cerevisiae
P06103
763
88111
N74
Y
K
V
T
E
E
F
N
F
D
Q
Y
I
V
V
Red Bread Mold
Neurospora crassa
Q7S464
747
85548
I79
G
K
T
R
E
D
L
I
F
M
P
M
G
E
D
Conservation
Percent
Protein Identity:
100
N.A.
98.5
88.3
N.A.
90.4
89.9
N.A.
80.5
N.A.
75.9
73
N.A.
44.9
50.4
24.6
55.4
Protein Similarity:
100
N.A.
98.8
90.5
N.A.
93.2
93.1
N.A.
82.9
N.A.
81.4
80.2
N.A.
60.4
66.3
42.2
70.1
P-Site Identity:
100
N.A.
73.3
33.3
N.A.
20
26.6
N.A.
0
N.A.
6.6
6.6
N.A.
6.6
0
20
13.3
P-Site Similarity:
100
N.A.
86.6
66.6
N.A.
40
46.6
N.A.
20
N.A.
13.3
20
N.A.
20
13.3
33.3
33.3
Percent
Protein Identity:
37.9
N.A.
N.A.
35.8
21.2
27.8
Protein Similarity:
57.6
N.A.
N.A.
56.8
42.1
48
P-Site Identity:
0
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
0
N.A.
N.A.
6.6
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
38
0
0
7
7
25
0
13
7
13
0
19
13
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
25
7
19
7
19
7
0
0
13
7
13
% D
% Glu:
25
19
0
0
13
38
0
7
7
7
25
7
13
19
0
% E
% Phe:
0
0
0
0
0
0
7
0
13
7
0
0
7
0
0
% F
% Gly:
7
0
0
7
19
0
0
0
7
7
7
0
13
13
19
% G
% His:
7
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
13
0
7
7
7
7
7
0
7
0
7
7
0
7
% I
% Lys:
7
19
7
7
0
0
7
0
7
7
7
19
13
7
7
% K
% Leu:
7
7
0
7
13
0
7
7
7
7
0
7
13
7
13
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
7
0
0
7
0
7
0
13
0
0
0
0
0
13
0
% N
% Pro:
0
7
13
0
0
25
7
7
7
13
13
13
0
7
7
% P
% Gln:
0
19
7
0
0
0
7
0
7
0
13
7
13
0
0
% Q
% Arg:
0
7
0
25
0
0
13
7
19
0
19
0
0
7
0
% R
% Ser:
0
7
7
0
0
0
7
13
0
13
0
7
7
0
0
% S
% Thr:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
25
7
19
38
19
13
13
13
13
13
7
13
7
7
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _