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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3B
All Species:
15.45
Human Site:
S152
Identified Species:
22.67
UniProt:
P55884
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55884
NP_001032360.1
814
92482
S152
N
G
D
A
D
E
P
S
F
S
D
P
E
D
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086876
814
92439
S152
N
G
D
A
D
E
P
S
F
S
D
P
E
D
F
Dog
Lupus familis
XP_850719
751
86022
E94
E
P
S
F
S
D
P
E
D
F
V
D
D
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ9
803
91352
S141
N
G
E
A
D
E
P
S
F
S
D
P
E
D
F
Rat
Rattus norvegicus
Q4G061
797
90892
S135
N
G
E
A
D
E
P
S
F
S
D
P
E
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513573
692
80444
G93
H
K
I
F
S
M
F
G
K
I
T
N
D
Y
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Q569Z1
688
80237
K92
K
I
F
S
K
F
G
K
L
T
N
E
F
Y
P
Zebra Danio
Brachydanio rerio
XP_001335480
681
79630
Y90
G
K
I
T
N
E
F
Y
P
D
A
D
G
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q0E940
690
80423
V93
Y
G
E
I
V
N
V
V
Y
P
V
D
E
E
G
Honey Bee
Apis mellifera
XP_393588
702
81532
K92
V
I
S
K
V
L
G
K
F
G
T
I
V
N
Q
Nematode Worm
Caenorhab. elegans
Q9XWI6
725
83129
S104
T
E
W
A
D
Q
R
S
A
Q
F
A
V
K
S
Sea Urchin
Strong. purpuratus
XP_001190551
703
81690
V95
L
K
N
V
I
R
K
V
C
S
K
Y
G
E
I
Poplar Tree
Populus trichocarpa
XP_002308719
719
82814
K92
Y
S
Q
I
G
V
I
K
E
D
G
L
W
M
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z1
712
81857
G92
L
G
V
I
K
E
N
G
L
W
M
P
V
D
P
Baker's Yeast
Sacchar. cerevisiae
P06103
763
88111
K108
S
L
F
S
K
A
G
K
V
V
N
M
E
F
P
Red Bread Mold
Neurospora crassa
Q7S464
747
85548
A105
S
S
P
A
E
A
A
A
A
C
R
Q
L
D
L
Conservation
Percent
Protein Identity:
100
N.A.
98.5
88.3
N.A.
90.4
89.9
N.A.
80.5
N.A.
75.9
73
N.A.
44.9
50.4
24.6
55.4
Protein Similarity:
100
N.A.
98.8
90.5
N.A.
93.2
93.1
N.A.
82.9
N.A.
81.4
80.2
N.A.
60.4
66.3
42.2
70.1
P-Site Identity:
100
N.A.
100
6.6
N.A.
93.3
93.3
N.A.
0
N.A.
0
6.6
N.A.
13.3
6.6
20
6.6
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
20
N.A.
20
13.3
N.A.
33.3
13.3
26.6
20
Percent
Protein Identity:
37.9
N.A.
N.A.
35.8
21.2
27.8
Protein Similarity:
57.6
N.A.
N.A.
56.8
42.1
48
P-Site Identity:
0
N.A.
N.A.
26.6
6.6
13.3
P-Site Similarity:
0
N.A.
N.A.
26.6
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
38
0
13
7
7
13
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% C
% Asp:
0
0
13
0
32
7
0
0
7
13
25
19
13
38
0
% D
% Glu:
7
7
19
0
7
38
0
7
7
0
0
7
38
13
0
% E
% Phe:
0
0
13
13
0
7
13
0
32
7
7
0
7
7
25
% F
% Gly:
7
38
0
0
7
0
19
13
0
7
7
0
13
0
7
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
13
19
7
0
7
0
0
7
0
7
0
0
7
% I
% Lys:
7
19
0
7
19
0
7
25
7
0
7
0
0
13
0
% K
% Leu:
13
7
0
0
0
7
0
0
13
0
0
7
7
0
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
7
7
0
7
0
% M
% Asn:
25
0
7
0
7
7
7
0
0
0
13
7
0
7
0
% N
% Pro:
0
7
7
0
0
0
32
0
7
7
0
32
0
0
25
% P
% Gln:
0
0
7
0
0
7
0
0
0
7
0
7
0
0
7
% Q
% Arg:
0
0
0
0
0
7
7
0
0
0
7
0
0
0
0
% R
% Ser:
13
13
13
13
13
0
0
32
0
32
0
0
0
0
13
% S
% Thr:
7
0
0
7
0
0
0
0
0
7
13
0
0
0
7
% T
% Val:
7
0
7
7
13
7
7
13
7
7
13
0
19
7
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
7
0
0
7
0
0
% W
% Tyr:
13
0
0
0
0
0
0
7
7
0
0
7
0
13
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _