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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3B
All Species:
27.27
Human Site:
S738
Identified Species:
40
UniProt:
P55884
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55884
NP_001032360.1
814
92482
S738
F
E
Q
K
D
R
L
S
Q
S
K
A
S
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086876
814
92439
S738
F
E
Q
K
D
R
L
S
Q
S
K
A
S
K
E
Dog
Lupus familis
XP_850719
751
86022
S675
F
E
Q
K
D
R
L
S
Q
S
K
A
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ9
803
91352
S727
F
E
Q
K
D
R
L
S
Q
S
K
A
S
K
E
Rat
Rattus norvegicus
Q4G061
797
90892
S721
F
E
Q
K
D
R
L
S
Q
S
K
A
S
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513573
692
80444
S616
F
E
Q
K
D
R
L
S
Q
S
K
A
S
K
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q569Z1
688
80237
S614
F
E
Q
K
D
R
L
S
Q
T
K
A
S
K
E
Zebra Danio
Brachydanio rerio
XP_001335480
681
79630
K609
K
D
R
L
S
Q
S
K
A
S
K
E
L
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q0E940
690
80423
L618
A
F
E
Q
K
D
R
L
R
L
T
R
A
S
K
Honey Bee
Apis mellifera
XP_393588
702
81532
R627
F
E
S
K
D
R
M
R
L
T
R
A
S
K
E
Nematode Worm
Caenorhab. elegans
Q9XWI6
725
83129
E645
F
I
K
Q
D
D
D
E
K
C
R
A
S
Q
E
Sea Urchin
Strong. purpuratus
XP_001190551
703
81690
K626
F
E
I
Q
D
A
K
K
K
S
K
A
S
K
E
Poplar Tree
Populus trichocarpa
XP_002308719
719
82814
V642
Y
E
A
E
D
Q
D
V
S
L
Q
L
S
E
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z1
712
81857
V638
Y
E
A
E
D
Q
D
V
S
L
L
L
S
E
Q
Baker's Yeast
Sacchar. cerevisiae
P06103
763
88111
D691
S
A
Q
F
E
E
Q
D
A
M
E
A
D
T
A
Red Bread Mold
Neurospora crassa
Q7S464
747
85548
R667
F
E
Q
E
D
A
E
R
I
S
S
A
D
V
A
Conservation
Percent
Protein Identity:
100
N.A.
98.5
88.3
N.A.
90.4
89.9
N.A.
80.5
N.A.
75.9
73
N.A.
44.9
50.4
24.6
55.4
Protein Similarity:
100
N.A.
98.8
90.5
N.A.
93.2
93.1
N.A.
82.9
N.A.
81.4
80.2
N.A.
60.4
66.3
42.2
70.1
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
13.3
N.A.
0
60
33.3
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
100
40
N.A.
33.3
80
66.6
73.3
Percent
Protein Identity:
37.9
N.A.
N.A.
35.8
21.2
27.8
Protein Similarity:
57.6
N.A.
N.A.
56.8
42.1
48
P-Site Identity:
20
N.A.
N.A.
20
13.3
40
P-Site Similarity:
60
N.A.
N.A.
53.3
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
13
0
0
13
0
0
13
0
0
75
7
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
0
0
82
13
19
7
0
0
0
0
13
0
7
% D
% Glu:
0
75
7
19
7
7
7
7
0
0
7
7
0
13
63
% E
% Phe:
69
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
7
0
7
50
7
0
7
13
13
0
57
0
0
57
7
% K
% Leu:
0
0
0
7
0
0
44
7
7
19
7
13
7
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
57
19
0
19
7
0
44
0
7
0
0
7
13
% Q
% Arg:
0
0
7
0
0
50
7
13
7
0
13
7
0
0
0
% R
% Ser:
7
0
7
0
7
0
7
44
13
57
7
0
75
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
13
7
0
0
7
0
% T
% Val:
0
0
0
0
0
0
0
13
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _