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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3B
All Species:
11.21
Human Site:
S81
Identified Species:
16.44
UniProt:
P55884
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55884
NP_001032360.1
814
92482
S81
A
E
A
A
S
G
P
S
E
S
P
S
P
P
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086876
814
92439
S81
A
E
A
A
F
G
P
S
E
S
L
S
P
P
A
Dog
Lupus familis
XP_850719
751
86022
G41
P
P
R
P
P
G
P
G
A
Q
E
A
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ9
803
91352
S75
S
E
E
E
T
A
T
S
P
A
A
S
P
T
P
Rat
Rattus norvegicus
Q4G061
797
90892
S75
S
E
E
E
T
A
A
S
P
A
A
S
P
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513573
692
80444
E40
A
I
G
P
Y
H
H
E
K
N
K
K
K
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q569Z1
688
80237
S40
E
G
F
E
D
D
I
S
D
E
E
L
L
G
D
Zebra Danio
Brachydanio rerio
XP_001335480
681
79630
G38
I
S
D
Q
E
L
L
G
D
V
L
R
D
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q0E940
690
80423
L41
N
I
S
D
E
D
L
L
G
D
M
L
A
Q
R
Honey Bee
Apis mellifera
XP_393588
702
81532
D40
S
D
P
E
G
F
I
D
D
I
T
D
E
E
L
Nematode Worm
Caenorhab. elegans
Q9XWI6
725
83129
E44
K
P
T
I
D
E
F
E
D
N
C
V
F
I
A
Sea Urchin
Strong. purpuratus
XP_001190551
703
81690
P41
E
E
P
D
F
S
D
P
E
S
Y
V
D
N
I
Poplar Tree
Populus trichocarpa
XP_002308719
719
82814
S40
G
D
D
F
G
V
I
S
D
D
E
D
V
Y
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z1
712
81857
E40
F
G
I
E
S
D
D
E
A
V
Y
Q
D
D
Q
Baker's Yeast
Sacchar. cerevisiae
P06103
763
88111
T42
S
K
I
I
Q
M
T
T
E
T
F
E
D
I
K
Red Bread Mold
Neurospora crassa
Q7S464
747
85548
L49
A
F
V
V
V
D
G
L
P
E
V
N
E
E
Q
Conservation
Percent
Protein Identity:
100
N.A.
98.5
88.3
N.A.
90.4
89.9
N.A.
80.5
N.A.
75.9
73
N.A.
44.9
50.4
24.6
55.4
Protein Similarity:
100
N.A.
98.8
90.5
N.A.
93.2
93.1
N.A.
82.9
N.A.
81.4
80.2
N.A.
60.4
66.3
42.2
70.1
P-Site Identity:
100
N.A.
86.6
13.3
N.A.
26.6
26.6
N.A.
6.6
N.A.
6.6
0
N.A.
0
0
6.6
20
P-Site Similarity:
100
N.A.
86.6
20
N.A.
46.6
46.6
N.A.
20
N.A.
13.3
6.6
N.A.
6.6
20
20
20
Percent
Protein Identity:
37.9
N.A.
N.A.
35.8
21.2
27.8
Protein Similarity:
57.6
N.A.
N.A.
56.8
42.1
48
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
20
N.A.
N.A.
6.6
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
13
13
0
13
7
0
13
13
13
7
13
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
13
13
13
13
25
13
7
32
13
0
13
25
7
7
% D
% Glu:
13
32
13
32
13
7
0
19
25
13
19
7
13
13
0
% E
% Phe:
7
7
7
7
13
7
7
0
0
0
7
0
7
0
0
% F
% Gly:
7
13
7
0
13
19
7
13
7
0
0
0
0
7
7
% G
% His:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
13
13
13
0
0
19
0
0
7
0
0
0
13
7
% I
% Lys:
7
7
0
0
0
0
0
0
7
0
7
7
7
7
7
% K
% Leu:
0
0
0
0
0
7
13
13
0
0
13
13
7
7
13
% L
% Met:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
13
0
7
0
7
0
% N
% Pro:
7
13
13
13
7
0
19
7
19
0
7
0
25
13
19
% P
% Gln:
0
0
0
7
7
0
0
0
0
7
0
7
0
7
19
% Q
% Arg:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
7
% R
% Ser:
25
7
7
0
13
7
0
38
0
19
0
25
0
7
0
% S
% Thr:
0
0
7
0
13
0
13
7
0
7
7
0
0
13
0
% T
% Val:
0
0
7
7
7
7
0
0
0
13
7
13
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
13
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _