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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3B
All Species:
28.79
Human Site:
Y760
Identified Species:
42.22
UniProt:
P55884
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55884
NP_001032360.1
814
92482
Y760
M
M
E
D
F
R
K
Y
R
K
M
A
Q
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086876
814
92439
Y760
M
M
E
D
F
R
K
Y
R
K
M
A
Q
E
L
Dog
Lupus familis
XP_850719
751
86022
Y697
M
M
E
D
F
R
K
Y
R
K
M
A
Q
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ9
803
91352
Y749
M
M
E
D
F
R
Q
Y
R
K
M
A
Q
E
L
Rat
Rattus norvegicus
Q4G061
797
90892
Y743
M
M
E
D
F
R
Q
Y
R
K
M
A
Q
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513573
692
80444
Y638
M
M
E
D
F
R
K
Y
R
K
M
A
Q
E
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q569Z1
688
80237
Y636
M
M
E
E
Y
K
T
Y
R
E
M
A
T
K
L
Zebra Danio
Brachydanio rerio
XP_001335480
681
79630
R631
E
Y
R
K
H
R
K
R
A
M
D
M
Y
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q0E940
690
80423
E640
Q
L
R
E
T
F
M
E
Y
R
N
K
R
I
A
Honey Bee
Apis mellifera
XP_393588
702
81532
Y649
A
M
K
A
F
E
E
Y
R
S
K
R
I
Q
E
Nematode Worm
Caenorhab. elegans
Q9XWI6
725
83129
I667
I
M
A
A
F
D
I
I
R
S
R
N
R
E
Q
Sea Urchin
Strong. purpuratus
XP_001190551
703
81690
I648
Q
M
N
D
F
K
E
I
V
E
R
M
K
K
R
Poplar Tree
Populus trichocarpa
XP_002308719
719
82814
W664
M
K
D
E
W
Y
K
W
V
N
E
W
K
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z1
712
81857
W660
L
K
E
E
W
E
K
W
V
M
Q
W
K
S
L
Baker's Yeast
Sacchar. cerevisiae
P06103
763
88111
W713
Q
R
E
L
L
K
Q
W
T
E
Y
R
E
K
I
Red Bread Mold
Neurospora crassa
Q7S464
747
85548
W689
L
L
E
E
W
F
A
W
R
E
A
I
R
Q
E
Conservation
Percent
Protein Identity:
100
N.A.
98.5
88.3
N.A.
90.4
89.9
N.A.
80.5
N.A.
75.9
73
N.A.
44.9
50.4
24.6
55.4
Protein Similarity:
100
N.A.
98.8
90.5
N.A.
93.2
93.1
N.A.
82.9
N.A.
81.4
80.2
N.A.
60.4
66.3
42.2
70.1
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
N.A.
53.3
13.3
N.A.
0
26.6
26.6
20
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
86.6
20
N.A.
26.6
46.6
40
53.3
Percent
Protein Identity:
37.9
N.A.
N.A.
35.8
21.2
27.8
Protein Similarity:
57.6
N.A.
N.A.
56.8
42.1
48
P-Site Identity:
20
N.A.
N.A.
20
6.6
13.3
P-Site Similarity:
53.3
N.A.
N.A.
53.3
53.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
13
0
0
7
0
7
0
7
44
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
44
0
7
0
0
0
0
7
0
0
0
0
% D
% Glu:
7
0
63
32
0
13
13
7
0
25
7
0
7
44
19
% E
% Phe:
0
0
0
0
57
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
13
0
0
0
7
7
7
7
% I
% Lys:
0
13
7
7
0
19
44
0
0
38
7
7
19
19
0
% K
% Leu:
13
13
0
7
7
0
0
0
0
0
0
0
0
7
57
% L
% Met:
50
63
0
0
0
0
7
0
0
13
44
13
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
7
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
0
0
0
0
19
0
0
0
7
0
38
19
7
% Q
% Arg:
0
7
13
0
0
44
0
7
63
7
13
13
19
0
7
% R
% Ser:
0
0
0
0
0
0
0
0
0
13
0
0
0
7
0
% S
% Thr:
0
0
0
0
7
0
7
0
7
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
19
0
0
25
0
0
0
13
0
0
0
% W
% Tyr:
0
7
0
0
7
7
0
50
7
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _