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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAG2
All Species:
28.18
Human Site:
T490
Identified Species:
77.5
UniProt:
P55895
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55895
NP_000527.2
527
59241
T490
E
I
A
R
A
L
H
T
P
Q
R
V
L
P
L
Chimpanzee
Pan troglodytes
XP_521889
527
59285
T490
E
I
A
R
A
L
H
T
P
Q
R
V
L
P
L
Rhesus Macaque
Macaca mulatta
XP_001114734
527
59338
T490
E
I
A
R
A
L
H
T
P
Q
R
V
L
P
L
Dog
Lupus familis
XP_540537
527
58801
T490
K
I
A
R
A
L
Q
T
P
K
R
A
P
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P21784
527
59055
T490
Q
I
A
R
A
L
Q
T
P
K
R
N
P
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509136
527
59319
T490
E
I
A
R
G
L
Q
T
P
K
K
M
L
P
V
Chicken
Gallus gallus
P25022
528
59071
T491
H
L
N
K
G
L
Q
T
P
K
K
A
V
H
L
Frog
Xenopus laevis
Q91830
520
58618
T483
E
V
A
R
G
V
Q
T
P
E
K
T
P
P
V
Zebra Danio
Brachydanio rerio
O13034
530
59155
T491
G
L
P
K
Q
E
M
T
P
P
K
Q
M
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.4
88.9
N.A.
88.4
N.A.
N.A.
78.9
72.5
61.6
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.2
94.5
N.A.
94.8
N.A.
N.A.
88.8
84
77.9
69.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
66.6
N.A.
N.A.
60
26.6
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
N.A.
N.A.
86.6
60
73.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
78
0
56
0
0
0
0
0
0
23
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
56
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
34
0
0
0
0
0
0
12
0
% H
% Ile:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
23
0
0
0
0
0
45
45
0
0
0
0
% K
% Leu:
0
23
0
0
0
78
0
0
0
0
0
0
45
12
67
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
12
12
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
100
12
0
0
34
78
12
% P
% Gln:
12
0
0
0
12
0
56
0
0
34
0
12
0
0
0
% Q
% Arg:
0
0
0
78
0
0
0
0
0
0
56
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
12
0
0
0
% T
% Val:
0
12
0
0
0
12
0
0
0
0
0
34
12
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _