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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAG2 All Species: 25.76
Human Site: Y346 Identified Species: 70.83
UniProt: P55895 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55895 NP_000527.2 527 59241 Y346 V S E G F Y F Y M L K C A E D
Chimpanzee Pan troglodytes XP_521889 527 59285 Y346 V S E G F Y F Y M L K C A E D
Rhesus Macaque Macaca mulatta XP_001114734 527 59338 Y346 V S E A F Y F Y T L K C A E E
Dog Lupus familis XP_540537 527 58801 Y346 T S E A F Y F Y M L K C A E D
Cat Felis silvestris
Mouse Mus musculus P21784 527 59055 Y346 M S E A F Y F Y T L R C S E E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509136 527 59319 Y346 I S D A N Y F Y I L K C G Q D
Chicken Gallus gallus P25022 528 59071 Y346 I S D A N Y F Y I L R C N K A
Frog Xenopus laevis Q91830 520 58618 C342 N K H Q S T D C S F F F Y V L
Zebra Danio Brachydanio rerio O13034 530 59155 Y346 P P E A Y H F Y Q V S F Q K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.4 88.9 N.A. 88.4 N.A. N.A. 78.9 72.5 61.6 51.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 99.2 94.5 N.A. 94.8 N.A. N.A. 88.8 84 77.9 69.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 80 86.6 N.A. 60 N.A. N.A. 53.3 40 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 86.6 N.A. 86.6 N.A. N.A. 80 73.3 0 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 67 0 0 0 0 0 0 0 0 45 0 12 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 0 78 0 0 0 % C
% Asp: 0 0 23 0 0 0 12 0 0 0 0 0 0 0 45 % D
% Glu: 0 0 67 0 0 0 0 0 0 0 0 0 0 56 34 % E
% Phe: 0 0 0 0 56 0 89 0 0 12 12 23 0 0 0 % F
% Gly: 0 0 0 23 0 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 12 0 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 23 0 0 0 0 0 0 0 23 0 0 0 0 0 0 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 56 0 0 23 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 78 0 0 0 0 12 % L
% Met: 12 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 23 0 0 0 0 0 0 0 12 0 0 % N
% Pro: 12 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 12 0 0 0 0 12 0 0 0 12 12 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 % R
% Ser: 0 78 0 0 12 0 0 0 12 0 12 0 12 0 0 % S
% Thr: 12 0 0 0 0 12 0 0 23 0 0 0 0 0 0 % T
% Val: 34 0 0 0 0 0 0 0 0 12 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 78 0 89 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _