KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GFRA1
All Species:
10.91
Human Site:
S408
Identified Species:
30
UniProt:
P56159
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56159
NP_001138925.1
465
51456
S408
Q
K
L
K
S
N
V
S
G
N
T
H
L
C
I
Chimpanzee
Pan troglodytes
XP_001150668
467
51638
S408
Q
K
L
K
S
N
V
S
G
N
T
H
L
C
I
Rhesus Macaque
Macaca mulatta
XP_001094722
530
56790
S471
Q
K
L
K
S
N
V
S
G
N
T
H
L
C
I
Dog
Lupus familis
XP_852087
468
51792
G409
K
L
K
S
N
M
S
G
S
T
H
L
C
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P97785
468
51764
G409
K
L
K
S
N
V
S
G
S
T
H
L
C
L
S
Rat
Rattus norvegicus
Q62997
468
51631
G409
K
L
K
S
N
V
S
G
S
T
H
L
C
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513939
304
33762
N248
R
S
N
K
S
Q
G
N
P
G
S
E
N
D
I
Chicken
Gallus gallus
O13156
469
52025
D409
R
K
S
N
E
S
V
D
T
E
L
C
L
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571805
472
52724
T416
I
Q
A
Q
K
K
K
T
N
N
T
I
D
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.2
94.4
N.A.
92.7
92.7
N.A.
53.3
78.2
N.A.
63.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
77.3
96.5
N.A.
96.1
96.5
N.A.
58
86.5
N.A.
77.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
20
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
40
33.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
34
34
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
12
12
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
12
0
12
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
34
34
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
34
34
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
45
% I
% Lys:
34
45
34
45
12
12
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
34
34
0
0
0
0
0
0
0
12
34
45
34
12
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
12
34
34
0
12
12
45
0
0
12
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% P
% Gln:
34
12
0
12
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
12
34
45
12
34
34
34
0
12
0
0
0
34
% S
% Thr:
0
0
0
0
0
0
0
12
12
34
45
0
0
0
0
% T
% Val:
0
0
0
0
0
23
45
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _