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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GFRA1
All Species:
31.52
Human Site:
Y235
Identified Species:
86.67
UniProt:
P56159
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56159
NP_001138925.1
465
51456
Y235
T
I
V
P
V
C
S
Y
E
E
R
E
K
P
N
Chimpanzee
Pan troglodytes
XP_001150668
467
51638
Y235
T
I
V
P
V
C
S
Y
E
E
R
E
K
P
N
Rhesus Macaque
Macaca mulatta
XP_001094722
530
56790
Y298
T
I
V
P
V
C
S
Y
E
E
R
E
K
P
N
Dog
Lupus familis
XP_852087
468
51792
Y235
T
I
V
P
V
C
S
Y
E
E
R
E
K
P
N
Cat
Felis silvestris
Mouse
Mus musculus
P97785
468
51764
Y235
T
I
V
P
V
C
S
Y
E
E
R
E
R
P
N
Rat
Rattus norvegicus
Q62997
468
51631
Y235
T
I
V
P
V
C
S
Y
E
E
R
E
R
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513939
304
33762
L79
P
K
H
S
Y
G
M
L
F
C
S
C
R
D
V
Chicken
Gallus gallus
O13156
469
52025
Y234
T
I
V
P
V
C
S
Y
E
D
R
E
K
P
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571805
472
52724
Y238
T
I
V
P
A
C
S
Y
E
D
K
E
R
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.2
94.4
N.A.
92.7
92.7
N.A.
53.3
78.2
N.A.
63.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
77.3
96.5
N.A.
96.1
96.5
N.A.
58
86.5
N.A.
77.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
93.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
89
0
0
0
12
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
23
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
89
67
0
89
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
89
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
12
0
56
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
89
% N
% Pro:
12
0
0
89
0
0
0
0
0
0
0
0
0
89
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
78
0
45
0
0
% R
% Ser:
0
0
0
12
0
0
89
0
0
0
12
0
0
0
0
% S
% Thr:
89
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
89
0
78
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
89
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _