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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARS
All Species:
13.94
Human Site:
S246
Identified Species:
27.88
UniProt:
P56192
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56192
NP_004981.2
900
101116
S246
A
W
E
K
G
L
E
S
L
P
P
L
R
P
Q
Chimpanzee
Pan troglodytes
XP_509164
900
101183
S246
A
W
E
K
G
L
E
S
L
P
P
L
R
P
Q
Rhesus Macaque
Macaca mulatta
XP_001116063
900
101127
S246
A
W
E
K
G
L
E
S
L
P
P
L
R
P
Q
Dog
Lupus familis
XP_849532
905
101818
S246
A
W
E
K
G
L
G
S
L
P
P
L
R
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q68FL6
902
101412
L246
V
A
A
W
E
K
G
L
E
S
L
P
P
L
K
Rat
Rattus norvegicus
NP_001121131
902
101563
L246
V
A
A
W
E
K
G
L
E
N
L
P
P
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515174
761
83752
S198
C
R
Y
F
F
L
L
S
G
W
E
Q
D
D
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PF21
905
102341
G244
A
W
A
K
G
L
T
G
A
S
K
P
K
Q
R
Zebra Danio
Brachydanio rerio
NP_956370
922
103504
D244
V
Y
S
E
G
L
K
D
F
T
V
V
T
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611382
1022
112466
K242
Y
T
A
P
K
E
I
K
E
E
R
T
V
L
P
Honey Bee
Apis mellifera
XP_397235
929
105695
P239
V
L
I
T
S
A
L
P
Y
V
N
N
V
P
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00958
751
85660
E188
T
V
K
P
K
D
S
E
I
L
P
K
P
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.1
93
N.A.
89.4
90.8
N.A.
55.8
N.A.
68.4
63.6
N.A.
44.4
46.8
N.A.
N.A.
Protein Similarity:
100
99.8
99.1
96.2
N.A.
94.1
94.6
N.A.
62
N.A.
81.6
76.7
N.A.
58.7
63.5
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
0
6.6
N.A.
13.3
N.A.
33.3
13.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
13.3
N.A.
46.6
46.6
N.A.
0
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
17
34
0
0
9
0
0
9
0
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
9
0
0
0
0
9
9
0
% D
% Glu:
0
0
34
9
17
9
25
9
25
9
9
0
0
9
9
% E
% Phe:
0
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
50
0
25
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
9
0
0
0
9
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
9
42
17
17
9
9
0
0
9
9
9
0
9
% K
% Leu:
0
9
0
0
0
59
17
17
34
9
17
34
0
25
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
9
9
0
9
0
% N
% Pro:
0
0
0
17
0
0
0
9
0
34
42
25
25
42
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
42
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
9
0
34
0
17
% R
% Ser:
0
0
9
0
9
0
9
42
0
17
0
0
0
0
0
% S
% Thr:
9
9
0
9
0
0
9
0
0
9
0
9
9
0
0
% T
% Val:
34
9
0
0
0
0
0
0
0
9
9
9
17
0
0
% V
% Trp:
0
42
0
17
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
9
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _