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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARS All Species: 21.21
Human Site: T122 Identified Species: 42.42
UniProt: P56192 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56192 NP_004981.2 900 101116 T122 G S V R R A L T H I D H S L S
Chimpanzee Pan troglodytes XP_509164 900 101183 T122 G S V R R A L T H I D H S L S
Rhesus Macaque Macaca mulatta XP_001116063 900 101127 T122 G S V R R A L T H I D H S L S
Dog Lupus familis XP_849532 905 101818 T122 G P V R R A L T H I D Y S L S
Cat Felis silvestris
Mouse Mus musculus Q68FL6 902 101412 T122 G P L R R V L T H I D H S L S
Rat Rattus norvegicus NP_001121131 902 101563 T122 G P L R R V L T H I D H S L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515174 761 83752 A74 V G F E V R G A S G A A A V P
Chicken Gallus gallus
Frog Xenopus laevis Q6PF21 905 102341 K120 A T I S A S L K H L D Q S L A
Zebra Danio Brachydanio rerio NP_956370 922 103504 W120 V M K E P L S W L E Q S L S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611382 1022 112466 K118 K K L D D K L K A T P Y L A G
Honey Bee Apis mellifera XP_397235 929 105695 V115 L L E E L N N V L K D K K Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00958 751 85660 I64 L L F D A N A I L R Y V M D D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.1 93 N.A. 89.4 90.8 N.A. 55.8 N.A. 68.4 63.6 N.A. 44.4 46.8 N.A. N.A.
Protein Similarity: 100 99.8 99.1 96.2 N.A. 94.1 94.6 N.A. 62 N.A. 81.6 76.7 N.A. 58.7 63.5 N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 0 N.A. 33.3 0 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 13.3 N.A. 66.6 0 N.A. 20 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 17 34 9 9 9 0 9 9 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 9 0 0 0 0 0 67 0 0 9 9 % D
% Glu: 0 0 9 25 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 9 0 0 0 0 9 0 0 9 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 59 0 0 42 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 9 0 50 0 0 0 0 0 % I
% Lys: 9 9 9 0 0 9 0 17 0 9 0 9 9 0 9 % K
% Leu: 17 17 25 0 9 9 67 0 25 9 0 0 17 59 9 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 17 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 25 0 0 9 0 0 0 0 0 9 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % Q
% Arg: 0 0 0 50 50 9 0 0 0 9 0 0 0 0 0 % R
% Ser: 0 25 0 9 0 9 9 0 9 0 0 9 59 9 50 % S
% Thr: 0 9 0 0 0 0 0 50 0 9 0 0 0 0 0 % T
% Val: 17 0 34 0 9 17 0 9 0 0 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 17 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _