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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARS
All Species:
16.97
Human Site:
T227
Identified Species:
33.94
UniProt:
P56192
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56192
NP_004981.2
900
101116
T227
P
E
E
E
E
L
A
T
L
S
E
E
E
I
A
Chimpanzee
Pan troglodytes
XP_509164
900
101183
T227
P
E
E
E
E
L
A
T
L
S
E
E
E
I
A
Rhesus Macaque
Macaca mulatta
XP_001116063
900
101127
T227
P
E
E
E
E
L
A
T
L
S
E
E
E
I
A
Dog
Lupus familis
XP_849532
905
101818
T227
P
E
E
E
E
L
A
T
L
S
E
E
E
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q68FL6
902
101412
L227
N
E
L
E
E
E
E
L
A
T
L
S
E
E
D
Rat
Rattus norvegicus
NP_001121131
902
101563
L227
N
E
P
E
E
E
E
L
A
T
L
S
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515174
761
83752
D179
R
V
P
A
L
E
L
D
G
G
G
F
L
F
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PF21
905
102341
S225
Q
E
G
E
D
M
P
S
L
S
E
E
D
I
Q
Zebra Danio
Brachydanio rerio
NP_956370
922
103504
E225
E
A
E
D
S
E
R
E
L
S
P
E
E
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611382
1022
112466
N223
T
V
A
D
T
V
T
N
E
E
I
S
A
A
K
Honey Bee
Apis mellifera
XP_397235
929
105695
P220
Y
P
D
V
K
N
F
P
Y
P
V
L
P
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00958
751
85660
K169
P
R
D
S
S
S
F
K
N
I
G
A
V
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.1
93
N.A.
89.4
90.8
N.A.
55.8
N.A.
68.4
63.6
N.A.
44.4
46.8
N.A.
N.A.
Protein Similarity:
100
99.8
99.1
96.2
N.A.
94.1
94.6
N.A.
62
N.A.
81.6
76.7
N.A.
58.7
63.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
26.6
26.6
N.A.
0
N.A.
46.6
40
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
33.3
33.3
N.A.
6.6
N.A.
73.3
46.6
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
0
34
0
17
0
0
9
9
9
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
17
9
0
0
9
0
0
0
0
9
0
17
% D
% Glu:
9
59
42
59
50
34
17
9
9
9
42
50
59
17
9
% E
% Phe:
0
0
0
0
0
0
17
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
9
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
9
0
0
50
9
% I
% Lys:
0
0
0
0
9
0
0
9
0
0
0
0
0
17
17
% K
% Leu:
0
0
9
0
9
34
9
17
50
0
17
9
9
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
9
0
9
9
0
0
0
0
0
0
% N
% Pro:
42
9
17
0
0
0
9
9
0
9
9
0
9
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
17
9
0
9
0
50
0
25
0
0
9
% S
% Thr:
9
0
0
0
9
0
9
34
0
17
0
0
0
0
0
% T
% Val:
0
17
0
9
0
9
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _