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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RX3
All Species:
23.03
Human Site:
T364
Identified Species:
56.3
UniProt:
P56373
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56373
NP_002550.2
397
44289
T364
K
F
E
E
V
N
E
T
T
L
K
I
A
A
L
Chimpanzee
Pan troglodytes
XP_001136930
397
44304
T364
K
F
E
E
V
N
E
T
T
L
K
I
A
A
L
Rhesus Macaque
Macaca mulatta
XP_001103269
397
44429
T364
K
F
E
E
V
N
E
T
T
L
K
I
A
A
L
Dog
Lupus familis
XP_540614
397
44272
T364
K
F
E
E
V
D
E
T
T
L
K
V
T
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UR32
397
44419
T364
K
F
E
E
V
T
E
T
T
L
K
G
T
A
S
Rat
Rattus norvegicus
P49654
397
44374
T364
K
F
E
E
V
T
E
T
T
L
K
G
T
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508992
486
53195
N454
K
Y
E
T
V
K
S
N
S
K
K
S
L
T
V
Chicken
Gallus gallus
XP_426413
408
44777
A372
K
F
E
E
V
P
E
A
S
V
S
P
A
P
T
Frog
Xenopus laevis
NP_001082067
391
44317
M356
V
A
T
V
L
C
D
M
I
V
F
H
F
F
K
Zebra Danio
Brachydanio rerio
NP_945337
412
46824
S374
K
F
E
E
V
S
D
S
N
I
K
S
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.9
94.7
N.A.
93.6
93.9
N.A.
34.7
68.8
45
66.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.9
96.7
N.A.
95.4
95.7
N.A.
51.6
81.8
63.4
79.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
73.3
73.3
N.A.
26.6
46.6
0
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
46.6
60
20
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
0
0
0
40
60
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
20
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
90
80
0
0
70
0
0
0
0
0
0
0
0
% E
% Phe:
0
80
0
0
0
0
0
0
0
0
10
0
10
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
20
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
30
0
0
0
% I
% Lys:
90
0
0
0
0
10
0
0
0
10
80
0
0
0
10
% K
% Leu:
0
0
0
0
10
0
0
0
0
60
0
0
10
0
30
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
30
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
10
10
20
0
10
20
10
0
40
% S
% Thr:
0
0
10
10
0
20
0
60
60
0
0
0
30
10
10
% T
% Val:
10
0
0
10
90
0
0
0
0
20
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _