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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTBP2
All Species:
26.67
Human Site:
S424
Identified Species:
41.9
UniProt:
P56545
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56545
NP_001077383.1
445
48945
S424
L
P
T
V
A
H
P
S
Q
A
P
S
P
N
Q
Chimpanzee
Pan troglodytes
XP_508100
956
103006
S935
L
P
T
V
A
H
P
S
Q
A
P
S
P
N
Q
Rhesus Macaque
Macaca mulatta
XP_001084451
992
106735
S971
L
P
T
V
A
H
P
S
Q
A
P
S
P
N
Q
Dog
Lupus familis
XP_855070
369
40480
T349
K
D
H
L
T
A
A
T
H
W
A
S
M
D
P
Cat
Felis silvestris
Mouse
Mus musculus
P56546
445
48938
S424
L
P
T
V
A
H
P
S
Q
A
P
S
P
N
Q
Rat
Rattus norvegicus
Q9EQH5
445
48968
S424
L
P
T
V
A
H
P
S
Q
A
P
S
P
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510652
503
54613
P481
L
P
A
V
A
H
P
P
H
A
P
S
P
S
Q
Chicken
Gallus gallus
XP_421817
978
105900
S957
L
P
T
V
A
H
P
S
Q
A
P
S
P
N
Q
Frog
Xenopus laevis
Q9YHU0
440
47758
P418
H
P
A
V
A
H
P
P
H
A
P
S
P
G
Q
Zebra Danio
Brachydanio rerio
NP_571790
444
48907
S423
L
P
P
G
T
Q
P
S
L
A
P
S
P
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46036
476
50719
N457
P
L
S
A
P
D
P
N
N
H
L
S
S
S
I
Honey Bee
Apis mellifera
XP_392682
472
49694
I456
L
T
G
I
P
H
S
I
V
S
E
P
D
P
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780717
442
48249
N422
H
S
M
P
M
P
M
N
V
V
S
T
P
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04130
624
66436
P495
R
M
V
V
D
S
S
P
E
Y
P
V
D
S
I
Baker's Yeast
Sacchar. cerevisiae
P40054
469
51175
D445
M
A
D
I
S
S
V
D
Q
S
D
I
K
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
44.6
70.7
N.A.
99.5
99.3
N.A.
71.1
43.9
77.9
88.7
N.A.
60.2
60.5
N.A.
65.3
Protein Similarity:
100
46.5
44.8
78.6
N.A.
99.7
99.5
N.A.
80.3
45
87.1
94.3
N.A.
72.6
73
N.A.
78.8
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
73.3
100
66.6
60
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
80
100
66.6
60
N.A.
33.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.8
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
7
54
7
7
0
0
60
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
7
7
0
7
0
0
7
0
14
14
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
7
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
14
0
7
0
0
60
0
0
20
7
0
0
0
0
0
% H
% Ile:
0
0
0
14
0
0
0
7
0
0
0
7
0
0
20
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% K
% Leu:
60
7
0
7
0
0
0
0
7
0
7
0
0
0
0
% L
% Met:
7
7
7
0
7
0
7
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
14
7
0
0
0
0
40
0
% N
% Pro:
7
60
7
7
14
7
67
20
0
0
67
7
67
7
7
% P
% Gln:
0
0
0
0
0
7
0
0
47
0
0
0
0
0
60
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
7
7
0
7
14
14
47
0
14
7
74
7
20
0
% S
% Thr:
0
7
40
0
14
0
0
7
0
0
0
7
0
7
0
% T
% Val:
0
0
7
60
0
0
7
0
14
7
0
7
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _