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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTBP2
All Species:
50.91
Human Site:
Y212
Identified Species:
80
UniProt:
P56545
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56545
NP_001077383.1
445
48945
Y212
S
V
I
F
Y
D
P
Y
L
Q
D
G
I
E
R
Chimpanzee
Pan troglodytes
XP_508100
956
103006
Y723
S
V
I
F
Y
D
P
Y
L
Q
D
G
I
E
R
Rhesus Macaque
Macaca mulatta
XP_001084451
992
106735
Y759
S
V
I
F
Y
D
P
Y
L
Q
D
G
I
E
R
Dog
Lupus familis
XP_855070
369
40480
I169
R
G
E
T
L
G
I
I
G
L
G
R
V
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
P56546
445
48938
Y212
S
V
I
F
Y
D
P
Y
L
Q
D
G
I
E
R
Rat
Rattus norvegicus
Q9EQH5
445
48968
Y212
S
V
I
F
Y
D
P
Y
L
Q
D
G
I
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510652
503
54613
Y268
N
V
I
F
Y
D
P
Y
L
S
D
G
I
E
R
Chicken
Gallus gallus
XP_421817
978
105900
Y745
N
V
I
F
Y
D
P
Y
L
Q
D
G
I
E
R
Frog
Xenopus laevis
Q9YHU0
440
47758
Y206
N
V
F
F
Y
D
P
Y
L
S
D
G
I
E
R
Zebra Danio
Brachydanio rerio
NP_571790
444
48907
Y212
N
V
I
F
Y
D
P
Y
L
Q
D
G
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46036
476
50719
Y206
N
V
I
F
Y
D
P
Y
L
P
D
G
I
D
K
Honey Bee
Apis mellifera
XP_392682
472
49694
Y207
T
V
I
F
Y
D
P
Y
L
P
D
G
I
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780717
442
48249
Y220
N
L
L
F
Y
D
P
Y
L
Q
D
G
M
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04130
624
66436
Y253
T
V
I
S
H
D
P
Y
A
P
A
D
R
A
R
Baker's Yeast
Sacchar. cerevisiae
P40054
469
51175
V230
H
V
L
Y
Y
D
I
V
T
I
M
A
L
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
44.6
70.7
N.A.
99.5
99.3
N.A.
71.1
43.9
77.9
88.7
N.A.
60.2
60.5
N.A.
65.3
Protein Similarity:
100
46.5
44.8
78.6
N.A.
99.7
99.5
N.A.
80.3
45
87.1
94.3
N.A.
72.6
73
N.A.
78.8
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
86.6
93.3
80
86.6
N.A.
73.3
80
N.A.
66.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
93.3
100
86.6
100
N.A.
93.3
93.3
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.8
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
7
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
94
0
0
0
0
80
7
0
7
0
% D
% Glu:
0
0
7
0
0
0
0
0
0
0
0
0
0
74
0
% E
% Phe:
0
0
7
80
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
7
0
0
7
0
7
80
0
14
0
% G
% His:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
74
0
0
0
14
7
0
7
0
0
67
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% K
% Leu:
0
7
14
0
7
0
0
0
80
7
0
0
14
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
87
0
0
20
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
7
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
7
7
0
67
% R
% Ser:
34
0
0
7
0
0
0
0
0
14
0
0
0
0
0
% S
% Thr:
14
0
0
7
0
0
0
0
7
0
0
0
0
0
7
% T
% Val:
0
87
0
0
0
0
0
7
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
87
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _