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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM50B All Species: 30.91
Human Site: S84 Identified Species: 56.67
UniProt: P56557 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56557 NP_006125.2 158 17936 S84 N A Q V R G D S Y E S G C L G
Chimpanzee Pan troglodytes XP_001137985 109 12091 S36 Q V R G D S Y S E G C L G Q T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535354 157 17353 S82 N G Q V R G D S Y S E G C L G
Cat Felis silvestris
Mouse Mus musculus Q9D1X9 158 17929 S84 N A Q V R G D S Y E S G C L G
Rat Rattus norvegicus NP_001120997 157 17375 S82 N G Q V R G D S Y S E G C L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512969 156 17503 S84 N A Q V R G D S Y G D G C L G
Chicken Gallus gallus XP_416711 158 17890 S84 N A Q V R G D S Y S D G C L G
Frog Xenopus laevis NP_001079839 158 17810 G84 N A Q V R G D G Y S D G C M G
Zebra Danio Brachydanio rerio NP_998694 164 18145 S85 N G Q V R G D S Y S E G C L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647888 152 16919 N78 G E H I S D E N S S E S G A R
Honey Bee Apis mellifera XP_624182 155 17167 A82 N A Q M R G D A L N G G Y L G
Nematode Worm Caenorhab. elegans NP_490985 157 17388 S81 N S Q V R G E S L H E G L L G
Sea Urchin Strong. purpuratus XP_783010 165 18104 S85 S G Q V R G D S Y G E G C M G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.2 N.A. 70.2 N.A. 98 70.2 N.A. 93.6 94.9 87.3 69.5 N.A. 36 46.8 50.6 61.2
Protein Similarity: 100 58.8 N.A. 82.2 N.A. 98 82.2 N.A. 94.9 98 93.6 83.5 N.A. 57.5 64.5 65.8 75.1
P-Site Identity: 100 6.6 N.A. 80 N.A. 100 80 N.A. 86.6 86.6 73.3 80 N.A. 0 60 60 66.6
P-Site Similarity: 100 13.3 N.A. 80 N.A. 100 80 N.A. 86.6 86.6 80 80 N.A. 20 73.3 73.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 47 0 0 0 0 0 8 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 70 0 0 % C
% Asp: 0 0 0 0 8 8 77 0 0 0 24 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 16 0 8 16 47 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 31 0 8 0 85 0 8 0 24 8 85 16 0 85 % G
% His: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 16 0 0 8 8 70 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 16 0 % M
% Asn: 77 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 85 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 85 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 8 8 0 0 8 8 0 77 8 47 16 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 0 8 0 77 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 70 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _