KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM50B
All Species:
42.73
Human Site:
T66
Identified Species:
78.33
UniProt:
P56557
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56557
NP_006125.2
158
17936
T66
H
T
C
G
V
F
S
T
L
A
F
F
M
I
N
Chimpanzee
Pan troglodytes
XP_001137985
109
12091
A18
C
G
V
I
A
T
I
A
F
L
M
I
N
A
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535354
157
17353
T64
H
A
C
G
V
I
A
T
I
A
F
L
M
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1X9
158
17929
T66
H
T
C
G
V
F
S
T
L
A
F
F
M
I
N
Rat
Rattus norvegicus
NP_001120997
157
17375
T64
H
A
C
G
V
I
A
T
I
A
F
L
M
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512969
156
17503
T66
H
T
C
G
V
F
S
T
L
A
F
F
M
I
N
Chicken
Gallus gallus
XP_416711
158
17890
T66
H
T
C
G
V
F
S
T
L
A
F
F
M
I
N
Frog
Xenopus laevis
NP_001079839
158
17810
T66
H
T
C
G
V
F
S
T
V
A
F
F
M
I
N
Zebra Danio
Brachydanio rerio
NP_998694
164
18145
T67
H
T
C
G
V
I
A
T
I
A
F
L
M
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647888
152
16919
T60
V
F
I
G
I
F
G
T
I
S
F
C
M
V
N
Honey Bee
Apis mellifera
XP_624182
155
17167
T64
H
V
C
G
I
F
G
T
I
S
L
F
M
I
N
Nematode Worm
Caenorhab. elegans
NP_490985
157
17388
T63
F
I
I
T
V
A
S
T
V
A
M
F
M
V
N
Sea Urchin
Strong. purpuratus
XP_783010
165
18104
T67
H
V
C
G
V
V
S
T
I
A
F
F
M
I
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
N.A.
70.2
N.A.
98
70.2
N.A.
93.6
94.9
87.3
69.5
N.A.
36
46.8
50.6
61.2
Protein Similarity:
100
58.8
N.A.
82.2
N.A.
98
82.2
N.A.
94.9
98
93.6
83.5
N.A.
57.5
64.5
65.8
75.1
P-Site Identity:
100
0
N.A.
66.6
N.A.
100
66.6
N.A.
100
100
93.3
73.3
N.A.
40
60
46.6
80
P-Site Similarity:
100
0
N.A.
80
N.A.
100
80
N.A.
100
100
100
86.6
N.A.
66.6
80
60
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
8
8
24
8
0
77
0
0
0
8
0
% A
% Cys:
8
0
77
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
54
0
0
8
0
77
62
0
0
0
% F
% Gly:
0
8
0
85
0
0
16
0
0
0
0
0
0
0
0
% G
% His:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
16
8
16
24
8
0
47
0
0
8
0
77
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
31
8
8
24
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
93
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
93
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
54
0
0
16
0
0
0
0
0
% S
% Thr:
0
47
0
8
0
8
0
93
0
0
0
0
0
0
0
% T
% Val:
8
16
8
0
77
8
0
0
16
0
0
0
0
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _