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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM50B
All Species:
28.48
Human Site:
Y48
Identified Species:
52.22
UniProt:
P56557
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56557
NP_006125.2
158
17936
Y48
M
I
D
A
A
V
V
Y
P
K
P
E
Q
L
N
Chimpanzee
Pan troglodytes
XP_001137985
109
12091
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535354
157
17353
Y46
I
I
D
A
A
V
I
Y
P
T
M
E
E
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1X9
158
17929
Y48
M
I
D
A
A
V
V
Y
P
K
P
E
Q
L
N
Rat
Rattus norvegicus
NP_001120997
157
17375
Y46
I
I
D
A
A
V
M
Y
P
N
M
E
Q
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512969
156
17503
Y48
M
I
D
A
A
V
V
Y
P
K
P
E
Q
M
N
Chicken
Gallus gallus
XP_416711
158
17890
Y48
M
I
D
A
A
V
V
Y
P
K
P
E
Q
M
N
Frog
Xenopus laevis
NP_001079839
158
17810
Y48
M
I
D
A
A
V
C
Y
P
D
Q
K
Q
L
N
Zebra Danio
Brachydanio rerio
NP_998694
164
18145
Y49
I
I
D
A
A
I
M
Y
P
K
E
E
Q
F
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647888
152
16919
I42
V
L
I
D
A
M
S
I
D
G
K
H
Q
I
T
Honey Bee
Apis mellifera
XP_624182
155
17167
A46
W
F
I
I
D
A
H
A
K
Y
P
N
E
M
A
Nematode Worm
Caenorhab. elegans
NP_490985
157
17388
V45
L
M
I
D
T
A
A
V
T
N
K
E
N
W
T
Sea Urchin
Strong. purpuratus
XP_783010
165
18104
F49
I
I
D
A
A
V
V
F
P
D
N
S
E
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
N.A.
70.2
N.A.
98
70.2
N.A.
93.6
94.9
87.3
69.5
N.A.
36
46.8
50.6
61.2
Protein Similarity:
100
58.8
N.A.
82.2
N.A.
98
82.2
N.A.
94.9
98
93.6
83.5
N.A.
57.5
64.5
65.8
75.1
P-Site Identity:
100
0
N.A.
60
N.A.
100
66.6
N.A.
93.3
93.3
73.3
60
N.A.
13.3
6.6
6.6
46.6
P-Site Similarity:
100
0
N.A.
80
N.A.
100
80
N.A.
100
100
80
86.6
N.A.
40
20
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
70
77
16
8
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
70
16
8
0
0
0
8
16
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
62
24
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
24
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% H
% Ile:
31
70
24
8
0
8
8
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
39
16
8
0
0
8
% K
% Leu:
8
8
0
0
0
0
0
0
0
0
0
0
0
24
0
% L
% Met:
39
8
0
0
0
8
16
0
0
0
16
0
0
31
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
16
8
8
8
0
54
% N
% Pro:
0
0
0
0
0
0
0
0
70
0
39
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
62
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
16
% T
% Val:
8
0
0
0
0
62
39
8
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _