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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM50B
All Species:
31.52
Human Site:
Y85
Identified Species:
57.78
UniProt:
P56557
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56557
NP_006125.2
158
17936
Y85
A
Q
V
R
G
D
S
Y
E
S
G
C
L
G
R
Chimpanzee
Pan troglodytes
XP_001137985
109
12091
E37
V
R
G
D
S
Y
S
E
G
C
L
G
Q
T
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535354
157
17353
Y83
G
Q
V
R
G
D
S
Y
S
E
G
C
L
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1X9
158
17929
Y85
A
Q
V
R
G
D
S
Y
E
S
G
C
L
G
R
Rat
Rattus norvegicus
NP_001120997
157
17375
Y83
G
Q
V
R
G
D
S
Y
S
E
G
C
L
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512969
156
17503
Y85
A
Q
V
R
G
D
S
Y
G
D
G
C
L
G
R
Chicken
Gallus gallus
XP_416711
158
17890
Y85
A
Q
V
R
G
D
S
Y
S
D
G
C
L
G
R
Frog
Xenopus laevis
NP_001079839
158
17810
Y85
A
Q
V
R
G
D
G
Y
S
D
G
C
M
G
R
Zebra Danio
Brachydanio rerio
NP_998694
164
18145
Y86
G
Q
V
R
G
D
S
Y
S
E
G
C
L
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647888
152
16919
S79
E
H
I
S
D
E
N
S
S
E
S
G
A
R
I
Honey Bee
Apis mellifera
XP_624182
155
17167
L83
A
Q
M
R
G
D
A
L
N
G
G
Y
L
G
A
Nematode Worm
Caenorhab. elegans
NP_490985
157
17388
L82
S
Q
V
R
G
E
S
L
H
E
G
L
L
G
T
Sea Urchin
Strong. purpuratus
XP_783010
165
18104
Y86
G
Q
V
R
G
D
S
Y
G
E
G
C
M
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
N.A.
70.2
N.A.
98
70.2
N.A.
93.6
94.9
87.3
69.5
N.A.
36
46.8
50.6
61.2
Protein Similarity:
100
58.8
N.A.
82.2
N.A.
98
82.2
N.A.
94.9
98
93.6
83.5
N.A.
57.5
64.5
65.8
75.1
P-Site Identity:
100
6.6
N.A.
73.3
N.A.
100
73.3
N.A.
86.6
86.6
73.3
73.3
N.A.
0
53.3
53.3
66.6
P-Site Similarity:
100
13.3
N.A.
80
N.A.
100
80
N.A.
86.6
86.6
80
80
N.A.
20
66.6
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
70
0
0
0
% C
% Asp:
0
0
0
8
8
77
0
0
0
24
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
16
0
8
16
47
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
31
0
8
0
85
0
8
0
24
8
85
16
0
85
8
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
16
0
0
8
8
70
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
85
0
0
0
0
0
0
0
0
0
0
8
0
31
% Q
% Arg:
0
8
0
85
0
0
0
0
0
0
0
0
0
8
39
% R
% Ser:
8
0
0
8
8
0
77
8
47
16
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% T
% Val:
8
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
70
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _