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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME5
All Species:
34.24
Human Site:
T108
Identified Species:
68.48
UniProt:
P56597
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56597
NP_003542.1
212
24236
T108
N
S
L
V
A
K
E
T
H
P
D
S
L
R
A
Chimpanzee
Pan troglodytes
XP_001170875
212
24185
T108
N
S
L
V
A
K
E
T
H
P
D
S
L
R
A
Rhesus Macaque
Macaca mulatta
XP_001112507
71
8120
Dog
Lupus familis
XP_853020
211
23885
T108
N
T
L
V
A
K
E
T
H
P
D
S
L
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99MH5
211
23983
T108
N
S
L
V
A
K
E
T
H
P
D
S
L
R
A
Rat
Rattus norvegicus
Q9QXL7
395
44521
E206
N
S
G
I
A
R
S
E
A
P
G
S
V
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521837
247
27735
T111
D
S
F
R
A
K
E
T
H
P
G
S
L
R
A
Chicken
Gallus gallus
XP_414687
212
24134
T108
N
S
I
K
A
R
M
T
H
P
H
S
L
R
A
Frog
Xenopus laevis
NP_001087794
219
24737
T114
N
S
L
K
A
K
E
T
Q
P
D
S
L
R
A
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
S105
K
V
F
R
A
R
F
S
S
P
E
T
L
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121989
325
37575
Y220
K
V
A
E
A
R
L
Y
Y
P
D
S
I
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790390
217
24732
T114
N
S
M
K
A
R
E
T
H
P
D
S
I
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
33.4
89.1
N.A.
85.8
23.2
N.A.
66.8
73.1
71.2
26.8
N.A.
N.A.
33.8
N.A.
62.2
Protein Similarity:
100
99.5
33.4
94.8
N.A.
94.3
37.2
N.A.
76.1
85.8
83.1
41.5
N.A.
N.A.
45.8
N.A.
81.5
P-Site Identity:
100
100
0
93.3
N.A.
100
46.6
N.A.
73.3
66.6
86.6
26.6
N.A.
N.A.
40
N.A.
73.3
P-Site Similarity:
100
100
0
100
N.A.
100
66.6
N.A.
80
80
86.6
53.3
N.A.
N.A.
60
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
92
0
0
0
9
0
0
0
0
0
84
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
59
9
0
0
9
0
0
0
0
% E
% Phe:
0
0
17
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
17
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
59
0
9
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
0
0
0
0
0
17
0
0
% I
% Lys:
17
0
0
25
0
50
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
42
0
0
0
9
0
0
0
0
0
67
0
0
% L
% Met:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
92
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
42
0
0
0
0
0
0
0
92
0
% R
% Ser:
0
67
0
0
0
0
9
9
9
0
0
84
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
67
0
0
0
9
0
0
0
% T
% Val:
0
17
0
34
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _