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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME5
All Species:
30.91
Human Site:
T119
Identified Species:
61.82
UniProt:
P56597
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56597
NP_003542.1
212
24236
T119
S
L
R
A
I
Y
G
T
D
D
L
R
N
A
L
Chimpanzee
Pan troglodytes
XP_001170875
212
24185
T119
S
L
R
A
I
Y
G
T
D
D
L
R
N
A
L
Rhesus Macaque
Macaca mulatta
XP_001112507
71
8120
D18
P
I
G
Q
A
A
K
D
Y
L
N
L
H
I
M
Dog
Lupus familis
XP_853020
211
23885
T119
S
L
R
A
I
Y
G
T
D
D
L
R
N
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99MH5
211
23983
T119
S
L
R
A
I
Y
G
T
D
E
L
R
N
A
L
Rat
Rattus norvegicus
Q9QXL7
395
44521
T217
S
V
R
A
L
F
G
T
D
G
I
R
N
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521837
247
27735
T122
S
L
R
A
I
Y
G
T
D
D
L
R
N
A
V
Chicken
Gallus gallus
XP_414687
212
24134
T119
S
L
R
A
I
Y
G
T
D
D
L
R
N
G
L
Frog
Xenopus laevis
NP_001087794
219
24737
T125
S
L
R
A
I
Y
G
T
D
D
L
R
N
A
L
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
L116
T
L
R
G
K
Y
G
L
T
D
T
R
N
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121989
325
37575
R231
S
I
R
A
R
Y
G
R
R
G
D
D
F
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790390
217
24732
I125
S
I
R
A
M
Y
G
I
D
D
Q
Q
N
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
33.4
89.1
N.A.
85.8
23.2
N.A.
66.8
73.1
71.2
26.8
N.A.
N.A.
33.8
N.A.
62.2
Protein Similarity:
100
99.5
33.4
94.8
N.A.
94.3
37.2
N.A.
76.1
85.8
83.1
41.5
N.A.
N.A.
45.8
N.A.
81.5
P-Site Identity:
100
100
0
100
N.A.
93.3
60
N.A.
93.3
93.3
100
46.6
N.A.
N.A.
33.3
N.A.
60
P-Site Similarity:
100
100
20
100
N.A.
100
86.6
N.A.
100
93.3
100
53.3
N.A.
N.A.
40
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
84
9
9
0
0
0
0
0
0
0
67
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
75
67
9
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
9
9
0
0
92
0
0
17
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
25
0
0
59
0
0
9
0
0
9
0
0
9
0
% I
% Lys:
0
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% K
% Leu:
0
67
0
0
9
0
0
9
0
9
59
9
0
0
50
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
84
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
9
9
0
0
0
% Q
% Arg:
0
0
92
0
9
0
0
9
9
0
0
75
0
0
0
% R
% Ser:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
67
9
0
9
0
0
9
9
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
84
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _