KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNQ4
All Species:
13.94
Human Site:
S444
Identified Species:
34.07
UniProt:
P56696
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56696
NP_004691.2
695
77101
S444
K
D
R
I
R
M
G
S
S
Q
R
R
T
G
P
Chimpanzee
Pan troglodytes
XP_513360
695
77068
S444
K
D
R
I
R
M
G
S
S
Q
R
R
T
G
P
Rhesus Macaque
Macaca mulatta
XP_001112016
932
102223
Q433
R
M
A
S
P
R
G
Q
S
I
K
S
R
Q
A
Dog
Lupus familis
XP_539568
611
68312
S361
D
R
I
R
M
G
S
S
Q
R
R
T
G
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JK97
696
77038
S445
K
D
R
I
R
I
S
S
S
Q
K
R
T
G
P
Rat
Rattus norvegicus
O88943
852
93931
S427
S
L
K
D
R
V
F
S
S
P
R
G
V
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507286
1026
107147
A775
E
L
P
D
G
P
P
A
R
Y
P
T
F
T
S
Chicken
Gallus gallus
XP_001233450
869
96177
S445
S
L
K
D
R
V
F
S
S
P
R
G
A
G
T
Frog
Xenopus laevis
P70057
377
42627
Y137
V
V
F
F
G
A
E
Y
V
V
R
L
W
S
A
Zebra Danio
Brachydanio rerio
XP_697081
974
106699
Q418
R
M
A
S
P
R
G
Q
S
I
K
S
R
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
38.9
85
N.A.
96.6
45
N.A.
41.8
44.9
29.9
37.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
52.4
86
N.A.
98.1
59
N.A.
50.6
57.8
38.5
49
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
80
26.6
N.A.
0
33.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
20
N.A.
93.3
40
N.A.
13.3
46.6
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
10
0
10
0
0
0
0
10
10
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
30
0
30
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
10
0
0
20
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
20
10
40
0
0
0
0
20
10
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
30
0
10
0
0
0
20
0
0
0
0
0
% I
% Lys:
30
0
20
0
0
0
0
0
0
0
30
0
0
0
0
% K
% Leu:
0
30
0
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
20
0
0
10
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
20
10
10
0
0
20
10
0
0
10
30
% P
% Gln:
0
0
0
0
0
0
0
20
10
30
0
0
0
20
0
% Q
% Arg:
20
10
30
10
50
20
0
0
10
10
60
30
20
0
0
% R
% Ser:
20
0
0
20
0
0
20
60
70
0
0
20
0
10
20
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
20
30
10
20
% T
% Val:
10
10
0
0
0
20
0
0
10
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _