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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNT3 All Species: 22.73
Human Site: S252 Identified Species: 50
UniProt: P56703 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56703 NP_110380.1 355 39645 S252 V V E K H R E S R G W V E T L
Chimpanzee Pan troglodytes Q2QLE7 360 40426 M246 N G A I Q V V M N Q D G T G F
Rhesus Macaque Macaca mulatta XP_001085785 352 39376 S249 V V E K H R E S R G W V E T L
Dog Lupus familis XP_850164 355 39657 S252 V V E K H R E S R G W V E T L
Cat Felis silvestris
Mouse Mus musculus P17553 355 39641 S252 V V E K H R E S R G W V E T L
Rat Rattus norvegicus Q9QXQ5 351 39025 R248 A T E V E P R R V G S S R A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus Q07DZ8 361 40096 M247 N G A I Q V V M N Q D G T G F
Chicken Gallus gallus Q2LMP1 352 39611 S249 V V E K H R E S R G W V E T L
Frog Xenopus laevis P31285 352 39697 S249 V V E K H R E S R G W V E T L
Zebra Danio Brachydanio rerio P47793 352 39413 K248 A T E V E L R K V G T T K V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790595 337 38170 G234 A V E R Q R K G R T F V E E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45 84.5 99.4 N.A. 98.8 48.7 N.A. 44.8 85.9 86.4 46.7 N.A. N.A. N.A. N.A. 51.2
Protein Similarity: 100 63.3 90.6 99.7 N.A. 99.4 65.3 N.A. 63.7 92.9 94 65.9 N.A. N.A. N.A. N.A. 66.4
P-Site Identity: 100 0 100 100 N.A. 100 20 N.A. 0 100 100 20 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 0 100 100 N.A. 100 20 N.A. 0 100 100 26.6 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 19 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % D
% Glu: 0 0 82 0 19 0 55 0 0 0 0 0 64 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 19 % F
% Gly: 0 19 0 0 0 0 0 10 0 73 0 19 0 19 0 % G
% His: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 55 0 0 10 10 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 82 % L
% Met: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % M
% Asn: 19 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 28 0 0 0 0 19 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 64 19 10 64 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 0 0 0 55 0 0 10 10 0 0 0 % S
% Thr: 0 19 0 0 0 0 0 0 0 10 10 10 19 55 0 % T
% Val: 55 64 0 19 0 19 19 0 19 0 0 64 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 55 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _