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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT3
All Species:
22.73
Human Site:
S252
Identified Species:
50
UniProt:
P56703
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56703
NP_110380.1
355
39645
S252
V
V
E
K
H
R
E
S
R
G
W
V
E
T
L
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
M246
N
G
A
I
Q
V
V
M
N
Q
D
G
T
G
F
Rhesus Macaque
Macaca mulatta
XP_001085785
352
39376
S249
V
V
E
K
H
R
E
S
R
G
W
V
E
T
L
Dog
Lupus familis
XP_850164
355
39657
S252
V
V
E
K
H
R
E
S
R
G
W
V
E
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P17553
355
39641
S252
V
V
E
K
H
R
E
S
R
G
W
V
E
T
L
Rat
Rattus norvegicus
Q9QXQ5
351
39025
R248
A
T
E
V
E
P
R
R
V
G
S
S
R
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
M247
N
G
A
I
Q
V
V
M
N
Q
D
G
T
G
F
Chicken
Gallus gallus
Q2LMP1
352
39611
S249
V
V
E
K
H
R
E
S
R
G
W
V
E
T
L
Frog
Xenopus laevis
P31285
352
39697
S249
V
V
E
K
H
R
E
S
R
G
W
V
E
T
L
Zebra Danio
Brachydanio rerio
P47793
352
39413
K248
A
T
E
V
E
L
R
K
V
G
T
T
K
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790595
337
38170
G234
A
V
E
R
Q
R
K
G
R
T
F
V
E
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45
84.5
99.4
N.A.
98.8
48.7
N.A.
44.8
85.9
86.4
46.7
N.A.
N.A.
N.A.
N.A.
51.2
Protein Similarity:
100
63.3
90.6
99.7
N.A.
99.4
65.3
N.A.
63.7
92.9
94
65.9
N.A.
N.A.
N.A.
N.A.
66.4
P-Site Identity:
100
0
100
100
N.A.
100
20
N.A.
0
100
100
20
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
0
100
100
N.A.
100
20
N.A.
0
100
100
26.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
19
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% D
% Glu:
0
0
82
0
19
0
55
0
0
0
0
0
64
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
19
% F
% Gly:
0
19
0
0
0
0
0
10
0
73
0
19
0
19
0
% G
% His:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
55
0
0
10
10
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
82
% L
% Met:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
28
0
0
0
0
19
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
64
19
10
64
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
55
0
0
10
10
0
0
0
% S
% Thr:
0
19
0
0
0
0
0
0
0
10
10
10
19
55
0
% T
% Val:
55
64
0
19
0
19
19
0
19
0
0
64
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
55
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _