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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNT3 All Species: 32.12
Human Site: T270 Identified Species: 70.67
UniProt: P56703 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56703 NP_110380.1 355 39645 T270 Y S L F K P P T E R D L V Y Y
Chimpanzee Pan troglodytes Q2QLE7 360 40426 T264 N E R F K K P T K N D L V Y F
Rhesus Macaque Macaca mulatta XP_001085785 352 39376 T267 Y T Y F K V P T E R D L V Y Y
Dog Lupus familis XP_850164 355 39657 T270 Y A L F K P P T E R D L V Y Y
Cat Felis silvestris
Mouse Mus musculus P17553 355 39641 T270 Y A L F K P P T E R D L V Y Y
Rat Rattus norvegicus Q9QXQ5 351 39025 T266 N A Q F K P H T D E D L V Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus Q07DZ8 361 40096 T265 N K R F K K P T K N D L V Y F
Chicken Gallus gallus Q2LMP1 352 39611 T267 Y N F F K A P T E K D L V Y Y
Frog Xenopus laevis P31285 352 39697 I267 Y T F F K P P I E R D L I Y Y
Zebra Danio Brachydanio rerio P47793 352 39413 T266 N S Q F K P H T D E D L V Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790595 337 38170 T252 Y D D F K E P T T N D L I Y Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45 84.5 99.4 N.A. 98.8 48.7 N.A. 44.8 85.9 86.4 46.7 N.A. N.A. N.A. N.A. 51.2
Protein Similarity: 100 63.3 90.6 99.7 N.A. 99.4 65.3 N.A. 63.7 92.9 94 65.9 N.A. N.A. N.A. N.A. 66.4
P-Site Identity: 100 53.3 80 93.3 N.A. 93.3 53.3 N.A. 53.3 73.3 73.3 60 N.A. N.A. N.A. N.A. 60
P-Site Similarity: 100 66.6 86.6 100 N.A. 100 66.6 N.A. 66.6 86.6 86.6 66.6 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 0 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 0 0 0 0 19 0 100 0 0 0 0 % D
% Glu: 0 10 0 0 0 10 0 0 55 19 0 0 0 0 0 % E
% Phe: 0 0 19 100 0 0 0 0 0 0 0 0 0 0 19 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 19 0 0 % I
% Lys: 0 10 0 0 100 19 0 0 19 10 0 0 0 0 0 % K
% Leu: 0 0 28 0 0 0 0 0 0 0 0 100 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 37 10 0 0 0 0 0 0 0 28 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 55 82 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 19 0 0 0 0 0 0 46 0 0 0 0 0 % R
% Ser: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 19 0 0 0 0 0 91 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 82 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 64 0 10 0 0 0 0 0 0 0 0 0 0 100 64 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _