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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT3A
All Species:
26.36
Human Site:
S181
Identified Species:
58
UniProt:
P56704
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56704
NP_149122.1
352
39365
S181
E
N
R
P
D
A
R
S
A
M
N
R
H
N
N
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
K180
D
A
K
E
R
K
G
K
D
A
R
A
L
M
N
Rhesus Macaque
Macaca mulatta
XP_001085785
352
39376
S181
E
N
R
P
D
A
R
S
A
M
N
R
H
N
N
Dog
Lupus familis
XP_539327
575
62713
S404
E
N
R
P
D
A
R
S
A
M
N
R
H
N
N
Cat
Felis silvestris
Mouse
Mus musculus
P27467
352
39239
S181
E
N
R
P
D
A
R
S
A
M
N
R
H
N
N
Rat
Rattus norvegicus
Q9QXQ5
351
39025
S181
E
R
S
K
G
A
S
S
S
R
A
L
M
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
K181
D
A
K
E
R
K
G
K
D
A
R
A
L
M
N
Chicken
Gallus gallus
Q2LMP1
352
39611
S181
E
N
R
P
D
A
R
S
A
M
N
R
H
N
N
Frog
Xenopus laevis
P31285
352
39697
S181
E
N
R
P
D
A
R
S
A
M
N
R
H
N
N
Zebra Danio
Brachydanio rerio
P24257
370
40992
Y195
E
R
G
R
D
L
R
Y
L
T
N
L
H
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790595
337
38170
A175
M
D
R
H
N
T
D
A
G
R
N
A
V
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
99.7
58.2
N.A.
96
48
N.A.
43.4
87.7
84
45.4
N.A.
N.A.
N.A.
N.A.
51.4
Protein Similarity:
100
62.5
99.7
60
N.A.
97.7
65.3
N.A.
61.7
92.9
91.1
58.9
N.A.
N.A.
N.A.
N.A.
66.1
P-Site Identity:
100
6.6
100
100
N.A.
100
26.6
N.A.
6.6
100
100
46.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
100
100
N.A.
100
33.3
N.A.
20
100
100
46.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
64
0
10
55
19
10
28
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
10
0
0
64
0
10
0
19
0
0
0
0
0
0
% D
% Glu:
73
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
19
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
64
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
19
10
0
19
0
19
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
10
0
0
19
19
10
10
% L
% Met:
10
0
0
0
0
0
0
0
0
55
0
0
10
19
0
% M
% Asn:
0
55
0
0
10
0
0
0
0
0
73
0
0
73
82
% N
% Pro:
0
0
0
55
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
64
10
19
0
64
0
0
19
19
55
0
0
0
% R
% Ser:
0
0
10
0
0
0
10
64
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _