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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT3A
All Species:
22.73
Human Site:
S237
Identified Species:
50
UniProt:
P56704
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56704
NP_149122.1
352
39365
S237
F
L
K
D
K
Y
D
S
A
S
E
M
V
V
E
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
G240
Y
L
W
R
K
Y
N
G
A
I
Q
V
V
M
N
Rhesus Macaque
Macaca mulatta
XP_001085785
352
39376
S237
F
L
K
D
K
Y
D
S
A
S
E
M
V
V
E
Dog
Lupus familis
XP_539327
575
62713
S460
F
L
K
D
K
Y
D
S
A
S
E
M
V
V
E
Cat
Felis silvestris
Mouse
Mus musculus
P27467
352
39239
S237
F
L
K
D
K
Y
D
S
A
S
E
M
V
V
E
Rat
Rattus norvegicus
Q9QXQ5
351
39025
G240
A
L
K
E
K
F
D
G
A
T
E
V
E
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
G241
Y
L
W
R
K
Y
N
G
A
I
Q
V
V
M
N
Chicken
Gallus gallus
Q2LMP1
352
39611
S237
Y
L
K
D
K
Y
D
S
A
S
E
M
V
V
E
Frog
Xenopus laevis
P31285
352
39697
S237
Y
L
K
D
K
Y
D
S
A
S
E
M
V
V
E
Zebra Danio
Brachydanio rerio
P24257
370
40992
G251
Y
L
K
D
R
F
D
G
A
S
R
V
V
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790595
337
38170
K233
M
A
V
E
R
Q
R
K
G
R
T
F
V
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
99.7
58.2
N.A.
96
48
N.A.
43.4
87.7
84
45.4
N.A.
N.A.
N.A.
N.A.
51.4
Protein Similarity:
100
62.5
99.7
60
N.A.
97.7
65.3
N.A.
61.7
92.9
91.1
58.9
N.A.
N.A.
N.A.
N.A.
66.1
P-Site Identity:
100
33.3
100
100
N.A.
100
40
N.A.
33.3
93.3
93.3
46.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
66.6
100
100
N.A.
100
66.6
N.A.
66.6
100
100
73.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
91
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
64
0
0
73
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
19
0
0
0
0
0
0
64
0
10
10
64
% E
% Phe:
37
0
0
0
0
19
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
37
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% I
% Lys:
0
0
73
0
82
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
91
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
55
0
19
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
19
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
19
0
0
0
0
% Q
% Arg:
0
0
0
19
19
0
10
0
0
10
10
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
55
0
64
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
37
91
55
0
% V
% Trp:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
46
0
0
0
0
73
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _