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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNT3A All Species: 24.24
Human Site: S300 Identified Species: 53.33
UniProt: P56704 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56704 NP_149122.1 352 39365 S300 R D R T C N V S S H G I D G C
Chimpanzee Pan troglodytes Q2QLE7 360 40426 S303 L T S R G M D S C E V M C C G
Rhesus Macaque Macaca mulatta XP_001085785 352 39376 S300 R D R T C N V S S H G I D G C
Dog Lupus familis XP_539327 575 62713 S523 R D R T C N V S S H G I D G C
Cat Felis silvestris
Mouse Mus musculus P27467 352 39239 S300 R D R T C N V S S H G I D G C
Rat Rattus norvegicus Q9QXQ5 351 39025 I303 C N K T S K A I D G C E L L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus Q07DZ8 361 40096 S304 L T S R G M D S C E V M C C G
Chicken Gallus gallus Q2LMP1 352 39611 T300 R D R I C N V T S H G I D G C
Frog Xenopus laevis P31285 352 39697 T300 R D R E C N V T S H G I D G C
Zebra Danio Brachydanio rerio P24257 370 40992 T314 T H G T S G R T C N S S S P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790595 337 38170 C296 I D G C E L L C C G R G H N T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.8 99.7 58.2 N.A. 96 48 N.A. 43.4 87.7 84 45.4 N.A. N.A. N.A. N.A. 51.4
Protein Similarity: 100 62.5 99.7 60 N.A. 97.7 65.3 N.A. 61.7 92.9 91.1 58.9 N.A. N.A. N.A. N.A. 66.1
P-Site Identity: 100 6.6 100 100 N.A. 100 13.3 N.A. 6.6 86.6 86.6 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 26.6 N.A. 13.3 93.3 93.3 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % A
% Cys: 10 0 0 10 55 0 0 10 37 0 10 0 19 19 64 % C
% Asp: 0 64 0 0 0 0 19 0 10 0 0 0 55 0 0 % D
% Glu: 0 0 0 10 10 0 0 0 0 19 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 19 0 19 10 0 0 0 19 55 10 0 55 19 % G
% His: 0 10 0 0 0 0 0 0 0 55 0 0 10 0 0 % H
% Ile: 10 0 0 10 0 0 0 10 0 0 0 55 0 0 0 % I
% Lys: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 19 0 0 0 0 10 10 0 0 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 19 0 0 0 0 0 19 0 0 0 % M
% Asn: 0 10 0 0 0 55 0 0 0 10 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 55 0 55 19 0 0 10 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 19 0 19 0 0 55 55 0 10 10 10 0 0 % S
% Thr: 10 19 0 55 0 0 0 28 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 55 0 0 0 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _