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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT3A
All Species:
22.42
Human Site:
Y273
Identified Species:
49.33
UniProt:
P56704
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56704
NP_149122.1
352
39365
Y273
P
T
E
R
D
L
V
Y
Y
E
A
S
P
N
F
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
D276
V
Y
F
E
N
S
P
D
Y
C
I
R
D
R
E
Rhesus Macaque
Macaca mulatta
XP_001085785
352
39376
Y273
P
T
E
R
D
L
V
Y
Y
E
A
S
P
N
F
Dog
Lupus familis
XP_539327
575
62713
Y496
P
T
E
R
D
L
V
Y
Y
E
A
S
P
N
F
Cat
Felis silvestris
Mouse
Mus musculus
P27467
352
39239
Y273
P
T
E
R
D
L
V
Y
Y
E
A
S
P
N
F
Rat
Rattus norvegicus
Q9QXQ5
351
39025
S276
D
L
V
Y
L
E
P
S
P
D
F
C
E
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
D277
V
Y
F
E
N
S
P
D
Y
C
I
K
D
R
D
Chicken
Gallus gallus
Q2LMP1
352
39611
Y273
P
T
E
K
D
L
V
Y
Y
E
N
S
P
N
F
Frog
Xenopus laevis
P31285
352
39697
Y273
P
I
E
R
D
L
I
Y
Y
E
S
S
P
N
F
Zebra Danio
Brachydanio rerio
P24257
370
40992
R287
A
H
K
L
P
S
S
R
D
L
V
Y
F
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790595
337
38170
D269
S
P
D
Y
C
T
F
D
Q
E
V
G
S
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
99.7
58.2
N.A.
96
48
N.A.
43.4
87.7
84
45.4
N.A.
N.A.
N.A.
N.A.
51.4
Protein Similarity:
100
62.5
99.7
60
N.A.
97.7
65.3
N.A.
61.7
92.9
91.1
58.9
N.A.
N.A.
N.A.
N.A.
66.1
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
6.6
86.6
80
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
6.6
N.A.
13.3
93.3
93.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
19
0
10
0
0
0
% C
% Asp:
10
0
10
0
55
0
0
28
10
10
0
0
19
0
19
% D
% Glu:
0
0
55
19
0
10
0
0
0
64
0
0
10
10
10
% E
% Phe:
0
0
19
0
0
0
10
0
0
0
10
0
10
10
55
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
10
0
0
0
19
0
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
10
0
10
10
55
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
10
0
0
55
0
% N
% Pro:
55
10
0
0
10
0
28
0
10
0
0
0
55
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
46
0
0
0
10
0
0
0
10
0
19
0
% R
% Ser:
10
0
0
0
0
28
10
10
0
0
10
55
10
0
0
% S
% Thr:
0
46
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
19
0
10
0
0
0
46
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
19
0
0
0
55
73
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _