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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNT4 All Species: 29.39
Human Site: S146 Identified Species: 64.67
UniProt: P56705 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56705 NP_110388.2 351 39052 S146 D R T V H G V S P Q G F Q W S
Chimpanzee Pan troglodytes Q2QLE7 360 40426 A145 D P K K M G S A K D S K G I F
Rhesus Macaque Macaca mulatta XP_001101962 380 42363 D172 S R A A R P K D L P R D W L W
Dog Lupus familis XP_855190 438 47738 S233 D R T V H G V S P Q G F Q W S
Cat Felis silvestris
Mouse Mus musculus P22724 351 39031 S146 D R T V H G V S P Q G F Q W S
Rat Rattus norvegicus Q9QXQ5 351 39025 S146 D R T V H G V S P Q G F Q W S
Wallaby Macropus eugenll
Platypus Ornith. anatinus Q07DZ8 361 40096 A146 D P K K K G S A K D S K G T F
Chicken Gallus gallus P49337 351 38945 S146 D R T V Q G G S P Q G F Q W S
Frog Xenopus laevis P49338 351 39148 S146 D R T V H G V S P Q G F Q W S
Zebra Danio Brachydanio rerio P47793 352 39413 S146 D R N V H G V S P E G F Q W S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786346 623 69928 S419 D R T V G G N S A D G F V W A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.3 46.5 78.5 N.A. 98.8 98.2 N.A. 48.7 85.4 85.4 82.3 N.A. N.A. N.A. N.A. 36.6
Protein Similarity: 100 65 63.1 79.2 N.A. 99.7 99.1 N.A. 65 92.8 94 93.4 N.A. N.A. N.A. N.A. 45.2
P-Site Identity: 100 13.3 6.6 100 N.A. 100 100 N.A. 13.3 86.6 100 86.6 N.A. N.A. N.A. N.A. 60
P-Site Similarity: 100 20 6.6 100 N.A. 100 100 N.A. 20 86.6 100 93.3 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 19 10 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 91 0 0 0 0 0 0 10 0 28 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 73 0 0 19 % F
% Gly: 0 0 0 0 10 91 10 0 0 0 73 0 19 0 0 % G
% His: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 19 19 10 0 10 0 19 0 0 19 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 19 0 0 0 10 0 0 64 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 55 0 0 64 0 0 % Q
% Arg: 0 82 0 0 10 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 19 73 0 0 19 0 0 0 64 % S
% Thr: 0 0 64 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 73 0 0 55 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 73 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _