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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNT4 All Species: 26.67
Human Site: S181 Identified Species: 58.67
UniProt: P56705 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56705 NP_110388.2 351 39052 S181 E R S K G A S S S R A L M N L
Chimpanzee Pan troglodytes Q2QLE7 360 40426 K180 D A K E R K G K D A R A L M N
Rhesus Macaque Macaca mulatta XP_001101962 380 42363 A207 R E R E R I H A K G S Y E S A
Dog Lupus familis XP_855190 438 47738 S268 E R S K G A S S S R A L M N L
Cat Felis silvestris
Mouse Mus musculus P22724 351 39031 S181 E R S K G A S S S R A L M N L
Rat Rattus norvegicus Q9QXQ5 351 39025 S181 E R S K G A S S S R A L M N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus Q07DZ8 361 40096 K181 D A K E R K G K D A R A L M N
Chicken Gallus gallus P49337 351 38945 S181 E R S K G A S S N R A L M N L
Frog Xenopus laevis P49338 351 39148 S181 E R S K G G S S S R A L M N L
Zebra Danio Brachydanio rerio P47793 352 39413 S181 E R S K G Q S S N R A L M N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786346 623 69928 L454 E R K T R A T L E R R L M N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.3 46.5 78.5 N.A. 98.8 98.2 N.A. 48.7 85.4 85.4 82.3 N.A. N.A. N.A. N.A. 36.6
Protein Similarity: 100 65 63.1 79.2 N.A. 99.7 99.1 N.A. 65 92.8 94 93.4 N.A. N.A. N.A. N.A. 45.2
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 0 93.3 93.3 86.6 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 20 26.6 100 N.A. 100 100 N.A. 20 100 93.3 93.3 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 55 0 10 0 19 64 19 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % D
% Glu: 73 10 0 28 0 0 0 0 10 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 64 10 19 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 28 64 0 19 0 19 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 0 73 19 0 73 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 73 19 0 % M
% Asn: 0 0 0 0 0 0 0 0 19 0 0 0 0 73 19 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 73 10 0 37 0 0 0 0 73 28 0 0 0 0 % R
% Ser: 0 0 64 0 0 0 64 64 46 0 10 0 0 10 0 % S
% Thr: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _